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ProNGF: a neurotrophic or an apoptotic molecule?
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Europe PubMed Central
PubMed publication ID
14699959
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
title
ProNGF: a neurotrophic or an apoptotic molecule?
(English)
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Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
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17 November 2019
main subject
apoptotic process
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author
Margaret Fahnestock
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1
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Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
author name string
Guanhua Yu
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2
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Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
Michael D Coughlin
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3
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Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
publication date
1 January 2004
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Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
published in
Progress in Brain Research
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
volume
146
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
page(s)
101-110
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
cites work
p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors
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7 January 2021
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Neurotrophic factors and their receptors
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Crossref
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7 January 2021
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Evidence for pro-β-nerve growth factor, a biosynthetic precursor to β-nerve growth factor
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Crossref
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7 January 2021
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Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR
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7 January 2021
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Nerve Growth Factor-induced p75-mediated Death of Cultured Hippocampal Neurons Is Age-dependent and Transduced through Ceramide Generated by Neutral Sphingomyelinase
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7 January 2021
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Nerve growth factor (NGF), proNGF and NGF receptor-like immunoreactivity in BB rat retina
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Crossref
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7 January 2021
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Characterization of nerve growth factor precursor protein expression in rat round spermatids and the trophic effects of nerve growth factor in the maintenance of Sertoli cell viability
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7 January 2021
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PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM.
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7 January 2021
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p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
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Characterization of nerve growth factor precursor protein expression by human prostate stromal cells: a role in selective neurotrophin stimulation of prostate epithelial cell growth
1 reference
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Crossref
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7 January 2021
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Interaction of antibodies to synthetic peptides of proNGF with in vitro synthesized NGF precursors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
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Nerve growth factor precursors in the rat thyroid and hippocampus
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Crossref
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7 January 2021
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Synthesis of nerve growth factor mRNA and precursor protein in the thyroid and parathyroid glands of the rat.
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7 January 2021
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Differential RNA splicing predicts two distinct nerve growth factor precursors
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Crossref
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7 January 2021
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Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector
1 reference
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Crossref
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7 January 2021
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The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
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Neurotrophins induce death of hippocampal neurons via the p75 receptor
1 reference
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https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophin signaling via Trks and p75.
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
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inferred from DOI database lookup
Enzymatic activities of mouse nerve growth factor and its subunits
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophic factors: from structure-function studies to designing effective therapeutics
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Emerging themes in structural biology of neurotrophic factors
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Jekyll-Hyde neurotrophins: the story of proNGF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The in vitro processing of the NGF precursors by the gamma-subunit of the 7S NGF complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophin signal transduction in the nervous system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the nerve growth factor carboxyl terminus in receptor binding and conformational stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Two restricted sites on the surface of the nerve growth factor molecule independently determine specific TrkA receptor binding and activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular forms of nerve growth factor in mouse submaxillary glands
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Biological actions of 53 kDa nerve growth factor as studied by a blot and culture technique
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Unexpected influence of a C-terminal-fused His-tag on the processing of an enzyme and on the kinetic and folding parameters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell survival by secreted proneurotrophins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nerve growth factor and proprotein convertases furin and PC7 in transected sciatic nerves and in nerve segments cultured in conditioned media: their presence in Schwann cells, macrophages, and smooth muscle cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kainic acid increases the expression of the prohormone convertases furin and PC1 in the mouse hippocampus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization and isolation of proteolytically modified nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid isolation of the 7S-nerve growth factor complex and its subunits from murine submaxillary glands and saliva
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Demonstration of a second pharmacologically active promoter region in the NGF gene that induces transcription at exon 3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pro-sequence facilitates folding of human nerve growth factor from Escherichia coli inclusion bodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-sequence assisted folding and disulfide bond formation of human nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Commercial recombinant human beta-nerve growth factor and adult rat dorsal root ganglia contain an identical molecular species of nerve growth factor prohormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A second determinant of binding to the p75 neurotrophin receptor revealed by alanine-scanning mutagenesis of a conserved loop in nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nerve growth factor: biosynthetic products of the mouse salivary glands. Characterization of stable high molecular weight and 32,000-dalton nerve growth factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse nerve growth factor gene: structure and expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterodimeric neurotrophins induce phosphorylation of Trk receptors and promote neuronal differentiation in PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human beta-nerve growth factor gene sequence highly homologous to that of mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of NH2-terminal residues of nerve growth factor affects activity and Trk binding without affecting stability or conformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of nerve growth factor mRNA and its translation products in the anagen hair follicle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular forms of NGF in human and rat neuropathic tissues: decreased NGF precursor-like immunoreactivity in human diabetic skin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2803%2946007-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0079-6123(03)46007-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
PubMed publication ID
14699959
1 reference
stated in
Europe PubMed Central
PubMed publication ID
14699959
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699959%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 November 2019
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