(Q34287799)

1 August 2017

title

Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity (English)

1 reference

1 August 2017

Kang Ho Kim

1

1 reference

1 August 2017

Gha Young Lee

2

1 reference

1 August 2017

Jong In Kim

3

1 reference

1 August 2017

Mira Ham

4

1 reference

1 August 2017

Joo Won Lee

5

1 reference

1 August 2017

Jae Bum Kim

6

1 reference

1 August 2017

publication date

16 September 2010

1 reference

Journal of Lipid Research

1 August 2017

published in

1 reference

1 August 2017

volume

51

1 reference

1 August 2017

issue

12

1 reference

1 August 2017

page(s)

3425-3433

1 reference

LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

1 August 2017

cites work

1 reference

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Fatty acid synthase is a novel therapeutic target in multiple myeloma

6 July 2018

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Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events

6 July 2018

1 reference

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Lipotoxic effects of triacylglycerols in J774.2 macrophages

6 July 2018

1 reference

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Modulation of liver X receptor signaling as novel therapy for prostate cancer

6 July 2018

1 reference

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Selective LXRalpha inhibitory effects observed in plant extracts of MEH184 (Parthenocissua tricuspidata) and MEH185 (Euscaphis japonica).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Liver X receptor preferentially activates de novo lipogenesis in human preadipocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

LXR-dependent gene expression is important for macrophage survival and the innate immune response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c

6 July 2018

1 reference

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Cellular and molecular mechanisms of atherosclerosis with mouse models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Putative metabolic effects of the liver X receptor (LXR).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells

6 July 2018

1 reference

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The liver X receptor gene team: potential new players in atherosclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Cyclin A in cell cycle control and cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Regulation of the Cdc25A gene by the human papillomavirus Type 16 E7 oncogene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Synthesis and antitumor activity of an inhibitor of fatty acid synthase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975714

Expression of the liver X receptor alpha and beta in embryonic and adult mice.

6 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Liver X receptor agonists suppress vascular smooth muscle cell proliferation and inhibit neointima formation in balloon-injured rat carotid arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

T0901317 is a dual LXR/FXR agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M007989

Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20847297

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20847297

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M007989

1 reference

1 August 2017

1 reference

1 August 2017

1 reference