(Q46299102)

21 December 2017

title

Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest (English)

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21 December 2017

author name string

Z X Meng

1

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21 December 2017

J Nie

2

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21 December 2017

J J Ling

3

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21 December 2017

J X Sun

4

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21 December 2017

Y X Zhu

5

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21 December 2017

L Gao

6

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21 December 2017

J H Lv

7

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21 December 2017

D Y Zhu

8

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21 December 2017

Y J Sun

9

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21 December 2017

X Han

10

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21 December 2017

publication date

24 October 2008

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21 December 2017

published in

Diabetologia

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21 December 2017

volume

52

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21 December 2017

page(s)

125-135

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21 December 2017

issue

1

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21 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-008-1174-x

exact match

0 references

cites work

Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression

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12 December 2020

The nuclear receptor LXR is a glucose sensor

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12 December 2020

DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water

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12 December 2020

Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells.

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12 December 2020

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

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12 December 2020

Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

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12 December 2020

The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse

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12 December 2020

p27 Regulates the transition of beta-cells from quiescence to proliferation.

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12 December 2020

Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.

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12 December 2020

Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells

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12 December 2020

Plasma oxysterols and tocopherol in patients with diabetes mellitus and hyperlipidemia

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12 December 2020

Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites

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12 December 2020

Prostaglandin E2 regulates Foxo activity via the Akt pathway: implications for pancreatic islet beta cell dysfunction

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12 December 2020

Intrinsic regulators of pancreatic beta-cell proliferation

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12 December 2020

Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion

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12 December 2020

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

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12 December 2020

Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus

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12 December 2020

T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR

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12 December 2020

Regulated beta-cell regeneration in the adult mouse pancreas.

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12 December 2020

The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver

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12 December 2020

Liver X receptor agonists suppress vascular smooth muscle cell proliferation and inhibit neointima formation in balloon-injured rat carotid arteries

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12 December 2020

IL-7 promotes T cell proliferation through destabilization of p27Kip1.

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12 December 2020

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

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12 December 2020

A simplified system for generating recombinant adenoviruses

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12 December 2020

Improved metabolic control by depletion of Liver X Receptors in mice

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12 December 2020

Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.

1 reference

12 December 2020

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

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12 December 2020

Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells

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12 December 2020

Putative metabolic effects of the liver X receptor (LXR).

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12 December 2020

Glucose-induced desensitization of the pancreatic beta-cell is species dependent

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12 December 2020

Functional and molecular defects of pancreatic islets in human type 2 diabetes

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12 December 2020

Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells

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12 December 2020

Cell cycle control of pancreatic beta cell proliferation

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12 December 2020

All beta cells contribute equally to islet growth and maintenance

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12 December 2020

Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.

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12 December 2020

Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels

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12 December 2020

Gene silencing by adenovirus-delivered siRNA.

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12 December 2020

Islet beta cell failure in type 2 diabetes

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12 December 2020

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

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12 December 2020

Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells

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12 December 2020

Molecular control of cell cycle progression in the pancreatic beta-cell

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12 December 2020

10.1007/S00125-008-1174-X

Identifiers

DOI

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21 December 2017

PubMed ID

18949453

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21 December 2017