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New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
scientific article (publication date: 23 February 2001)
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
main subject
pathogenesis
1 reference
based on heuristic
inferred from title
type 2 diabetes
0 references
author
Alan R. Saltiel
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author name string
A R Saltiel
series ordinal
1
0 references
language of work or name
English
0 references
publication date
1 February 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
104
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
517-529
1 reference
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
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Role of brain insulin receptor in control of body weight and reproduction
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Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
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ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose
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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
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Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice
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Perinuclear localization and insulin responsiveness of GLUT4 requires cytoskeletal integrity in 3T3-L1 adipocytes
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A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.
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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
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Membrane-permeant esters of phosphatidylinositol 3,4,5-trisphosphate
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Crossref
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7 January 2021
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Obesity and insulin resistance
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Crossref
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7 January 2021
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Gestational diabetes mellitus
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7 January 2021
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Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
1 reference
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Crossref
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Regional adiposity and morbidity
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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma
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Two Naturally Occurring Insulin Receptor Tyrosine Kinase Domain Mutants Provide Evidence That Phosphoinositide 3-Kinase Activation Alone Is Not Sufficient for the Mediation of Insulin’s Metabolic and Mitogenic Effects
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PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
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Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.
1 reference
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New insights into the role and mechanism of glycogen synthase activation by insulin
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7 January 2021
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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
1 reference
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NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds
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Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells
1 reference
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Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction
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Synip
1 reference
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7 January 2021
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Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1
1 reference
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
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Regulation of gene expression by insulin
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7 January 2021
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Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM.
1 reference
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7 January 2021
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PPAR gamma and the treatment of insulin resistance
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7 January 2021
based on heuristic
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TNF-alpha and insulin resistance: summary and future prospects
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Crossref
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7 January 2021
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Searching for type 2 diabetes genes in the post-genome era.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
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Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.
1 reference
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
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Signaling pathways in insulin action: molecular targets of insulin resistance
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Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location!
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7 January 2021
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13C/31P NMR studies on the mechanism of insulin resistance in obesity
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7 January 2021
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Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
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7 January 2021
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Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs
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7 January 2021
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Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
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Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
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Mechanism of free fatty acid-induced insulin resistance in humans
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thiazolidinediones in the treatment of insulin resistance and type II diabetes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Obesity and diabetes in TNF-alpha receptor- deficient mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Asp905Tyr polymorphism of the gene for the skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in NIDDM.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Direct antidiabetic effect of leptin through triglyceride depletion of tissues.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular mechanisms of insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Obesity and the regulation of energy balance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hormone resistin links obesity to diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syndromes associated with insulin resistance and acanthosis nigricans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of fatty acid homeostasis in cells: novel role of leptin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the Src homology 2 (SH2) domain and C-terminus tyrosine phosphorylation sites of SH2-containing inositol phosphatase (SHIP) in the regulation of insulin-induced mitogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of IRS-2 causes type 2 diabetes in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900239-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(01)00239-2
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1550015
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
OpenCitations bibliographic resource ID
1550015
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1550015
PubMed ID
11239409
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1550015
stated in
Europe PubMed Central
PubMed ID
11239409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
ResearchGate publication ID
12093423
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