(Q34288117)

1 August 2017

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title

Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model (English)

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steroid hormone receptor activity

1 August 2017

main subject

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Gene Ontology release 2020-05-02

Anthony W Norman

1

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1 August 2017

Mathew T Mizwicki

series ordinal

2

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1 August 2017

Derek P G Norman

series ordinal

3

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1 August 2017

publication date

1 January 2004

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Nature Reviews Drug Discovery

1 August 2017

published in

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1 August 2017

volume

3

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1 August 2017

issue

1

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1 August 2017

page(s)

27-41

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Intracellular calcium increase and acrosome reaction in response to progesterone in human spermatozoa are correlated with in-vitro fertilization.

1 August 2017

cites work

1 reference

Progesterone triggers a wave of increased free calcium during the human sperm acrosome reaction

31 March 2020

1 reference

1alpha,25(OH)2D3 regulates chondrocyte matrix vesicle protein kinase C (PKC) directly via G-protein-dependent mechanisms and indirectly via incorporation of PKC during matrix vesicle biogenesis

31 March 2020

1 reference

RETARDATION OF SODIUM EXCHANGE IN DOG ERYTHROCYTES BY PHYSIOLOGICAL CONCENTRATIONS OF ALDOSTERONE, IN VITRO.

31 March 2020

1 reference

A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization

31 March 2020

1 reference

A putative leucine-rich repeat receptor kinase involved in brassinosteroid signal transduction

31 March 2020

1 reference

A mathematical model describing the subcellular localization of non-membrane bound steroid, seco-steroid and thyronine receptors

31 March 2020

1 reference

Nuclear receptor coregulators: multiple modes of modification

31 March 2020

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Combinatorial control of gene expression by nuclear receptors and coregulators

31 March 2020

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Nuclear receptors in cell life and death.

31 March 2020

1 reference

The nuclear receptor ligand-binding domain: structure and function

31 March 2020

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Nuclear-receptor ligands and ligand-binding domains

31 March 2020

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Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

31 March 2020

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Ligand-protein interactions in nuclear receptors of hormones.

31 March 2020

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Chromosomal receptor for a vitamin D metabolite

31 March 2020

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Natural ligands of nuclear receptors have conserved volumes

31 March 2020

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Molecular tools for study of genomic and rapid signal transduction responses initiated by 1 alpha,25(OH)(2)-vitamin D(3).

31 March 2020

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Reversal of bone loss in mice by nongenotropic signaling of sex steroids

31 March 2020

1 reference

Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor.

31 March 2020

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Antagonists selective for estrogen receptor alpha

31 March 2020

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Rational design of vitamin D3 analogues which selectively restore activity to a vitamin D receptor mutant associated with rickets.

31 March 2020

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A role for lipid shells in targeting proteins to caveolae, rafts, and other lipid domains

31 March 2020

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Caveolae: from cell biology to animal physiology

31 March 2020

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Perception of brassinosteroids by the extracellular domain of the receptor kinase BRI1.

31 March 2020

1 reference

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes

31 March 2020

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Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor

31 March 2020

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A specific binding protein/receptor for 1alpha,25-dihydroxyvitamin D(3) is present in an intestinal caveolae membrane fraction

31 March 2020

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Rapid effects of aldosterone and spironolactone in the isolated working rat heart

31 March 2020

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Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases

31 March 2020

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Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane

31 March 2020

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Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Galpha(i).

31 March 2020

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Proximal events in signaling by plasma membrane estrogen receptors

31 March 2020

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Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action

31 March 2020

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Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane

31 March 2020

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Elastase controls the binding of the vitamin D-binding protein (Gc-globulin) to neutrophils: a potential role in the regulation of C5a co-chemotactic activity

31 March 2020

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Non-genomic convergent and divergent signalling of rapid responses to aldosterone and estradiol in mammalian colon

31 March 2020

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Direct activation of protein kinase C by 1 alpha,25-dihydroxyvitamin D3

31 March 2020

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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

31 March 2020

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Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

31 March 2020

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Orphan nuclear receptors: shifting endocrinology into reverse

31 March 2020

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Molecular basis of agonism and antagonism in the oestrogen receptor

31 March 2020

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Two Key Proteins of the Vitamin D Endocrine System Come Into Crystal Clear Focus: Comparison of the X‐ray Structures of the Nuclear Receptor for 1α,25(OH)2 Vitamin D3, the Plasma Vitamin D Binding Protein, and Their Ligands

31 March 2020

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Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain

31 March 2020

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Structure/function analyses of human sex hormone-binding globulin: effects of zinc on steroid-binding specificity

31 March 2020

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A structural role for hormone in the thyroid hormone receptor.

31 March 2020

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Einfluss der Configuration auf die Wirkung der Enzyme

31 March 2020

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Application of a Theory of Enzyme Specificity to Protein Synthesis

31 March 2020

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Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles.

31 March 2020

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Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels

31 March 2020

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OmpA: a pore or not a pore? Simulation and modeling studies

31 March 2020

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A guide to drug discovery: Target selection in drug discovery

31 March 2020

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Endometrial cell calcium and oestrogen action

31 March 2020

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Acute activation of Maxi-K channels (hSlo) by estradiol binding to the beta subunit

31 March 2020

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Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

31 March 2020

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Plasma membrane estrogen receptors signal to antiapoptosis in breast cancer

31 March 2020

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Functional testosterone receptors in plasma membranes of T cells.

31 March 2020

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Testosterone induces Ca2+ influx via non-genomic surface receptors in activated T cells

31 March 2020

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Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

31 March 2020

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Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells

31 March 2020

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The classical progesterone receptor associates with p42 MAPK and is involved in phosphatidylinositol 3-kinase signaling in Xenopus oocytes

31 March 2020

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Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

31 March 2020

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Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells

31 March 2020

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Stimulation by 1alpha,25(OH)2-vitamin D3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells. A structure-function study

31 March 2020

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1alpha,25-dihydroxyvitamin D3 induces vascular smooth muscle cell migration via activation of phosphatidylinositol 3-kinase

31 March 2020

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An insulinotropic effect of vitamin D analog with increasing intracellular Ca2+ concentration in pancreatic beta-cells through nongenomic signal transduction

31 March 2020

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Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor

31 March 2020

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Monocytic Differentiation of Acute Promyelocytic Leukemia Cells in Response to 1,25-Dihydroxyvitamin D3 Is Independent of Nuclear Receptor Binding

31 March 2020

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Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25-dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: a structure-function study

31 March 2020

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Nongenomic mechanisms of glucocorticoid inhibition of nicotine-induced calcium influx in PC12 cells: involvement of protein kinase C

31 March 2020

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A corticosteroid receptor in neuronal membranes.

31 March 2020

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Potentiation by thyroxine of interferon-gamma-induced antiviral state requires PKA and PKC activities

31 March 2020

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Effects of thyroid hormone on action potential and repolarizing currents in rat ventricular myocytes

31 March 2020

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Nongenomic actions of thyroid hormone on the heart

31 March 2020

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Cellular functions of plasma membrane estrogen receptors

31 March 2020

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Nongenomic steroid action: controversies, questions, and answers

31 March 2020

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RETRACTED: Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade

31 March 2020

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A vitamin D receptor-Ser/Thr phosphatase-p70 S6 kinase complex and modulation of its enzymatic activities by the ligand

31 March 2020

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Partial purification and biochemical characterization of a membrane glucocorticoid receptor from an amphibian brain

31 March 2020

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Immunoaffinity isolation of native membrane glucocorticoid receptor from S-49++ lymphoma cells: biochemical characterization and interaction with Hsp 70 and Hsp 90

31 March 2020

1 reference

Immunochemical studies on the putative plasmalemmal receptor for 1, 25(OH)(2)D(3). I. Chick intestine

31 March 2020

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Evidence for distinct membrane receptors for 1 alpha,25-(OH)(2)D(3) and 24R,25-(OH)(2)D(3) in osteoblasts

31 March 2020

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Characterization of membrane nongenomic receptors for progesterone in human spermatozoa

31 March 2020

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Estrogen receptor-alpha detected on the plasma membrane of aldehyde-fixed GH3/B6/F10 rat pituitary tumor cells by enzyme-linked immunocytochemistry

31 March 2020

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Selective modulation of genomic and nongenomic androgen responses by androgen receptor ligands

31 March 2020

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Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells

31 March 2020

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Non-classical receptors for aldosterone in plasma membranes from pig kidneys

31 March 2020

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The human prostate cancer cell line LNCaP bears functional membrane testosterone receptors that increase PSA secretion and modify actin cytoskeleton

31 March 2020

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The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

31 March 2020

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A structural basis for the unique binding features of the human vitamin D-binding protein

31 March 2020

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Different shapes of the steroid hormone 1alpha,25(OH)(2)-vitamin D(3) act as agonists for two different receptors in the vitamin D endocrine system to mediate genomic and rapid responses

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRD1283

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1 August 2017

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