(Q34292544)

1 August 2017

Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics (English)

1 reference

1 August 2017

1 reference

Y Shu

1

1 reference

1 August 2017

C Brown

2

1 reference

1 August 2017

R A Castro

3

1 reference

1 August 2017

R J Shi

4

1 reference

1 August 2017

E T Lin

5

1 reference

1 August 2017

R P Owen

6

1 reference

1 August 2017

S A Sheardown

7

1 reference

1 August 2017

L Yue

8

1 reference

1 August 2017

E G Burchard

9

1 reference

1 August 2017

C M Brett

10

1 reference

1 August 2017

K M Giacomini

11

1 reference

1 August 2017

language of work or name

English

0 references

publication date

4 July 2007

1 reference

Clinical Pharmacology & Therapeutics

1 August 2017

1 reference

1 August 2017

83

1 reference

1 August 2017

273-280

1 reference

1 August 2017

2

1 reference

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Organic cation transporters are determinants of oxaliplatin cytotoxicity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Transporters and drug discovery: why, when, and how.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

A gene atlas of the mouse and human protein-encoding transcriptomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Cloning and characterization of two human polyspecific organic cation transporters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Cloning and functional expression of a human liver organic cation transporter

6 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

6 July 2018

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100275

inferred from DOI database lookup

7 January 2021

based on heuristic

Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Clinical pharmacokinetics of metformin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Drug excretion mediated by a new prototype of polyspecific transporter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Metformin kinetics in healthy subjects and in patients with diabetes mellitus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Disposition of metformin (N,N-dimethylbiguanide) in man.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Pharmacokinetics of metformin after intravenous and oral administration to man

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100275

Measurement of the renal clearance of drugs

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100275

Estimating the contribution of genes and environment to variation in renal drug clearance

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976713

28 October 2018

Identifiers

DOI

10.1038/SJ.CLPT.6100275

1 reference

1 August 2017

1 reference

1 August 2017

1 reference