(Q35762110)

10 August 2017

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action (English)

1 reference

10 August 2017

1 reference

1 reference

10

Esteban G Burchard

1 reference

10 August 2017

Yan Shu

1

1 reference

10 August 2017

Steven A Sheardown

2

1 reference

10 August 2017

Chaline Brown

3

1 reference

10 August 2017

Ryan P Owen

4

1 reference

10 August 2017

Shuzhong Zhang

5

1 reference

10 August 2017

Richard A Castro

6

1 reference

10 August 2017

Alexandra G Ianculescu

7

1 reference

10 August 2017

Lin Yue

8

1 reference

10 August 2017

Joan C Lo

9

1 reference

10 August 2017

Claire M Brett

11

1 reference

10 August 2017

Kathleen M Giacomini

12

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 May 2007

1 reference

Journal of Clinical Investigation

10 August 2017

1 reference

10 August 2017

117

1 reference

10 August 2017

5

1 reference

10 August 2017

1422-1431

1 reference

Organic cation transporters are determinants of oxaliplatin cytotoxicity.

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Functional genomics of membrane transporters in human populations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Regulation of glucose transport by the AMP-activated protein kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Insulin sensitizers for polycystic ovary syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Natural variation in human membrane transporter genes reveals evolutionary and functional constraints

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Role of AMP-activated protein kinase in mechanism of metformin action

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

The effects of AICAR on adipocyte differentiation of 3T3-L1 cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Metformin reverses fatty liver disease in obese, leptin-deficient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Stimulation of AMP-activated protein kinase (AMPK) is associated with enhancement of Glut1-mediated glucose transport

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Cloning and functional expression of a human liver organic cation transporter

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Metformin: a review of its pharmacological properties and therapeutic use

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Estimating the contribution of genes and environment to variation in renal drug clearance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations. A double-blind controlled study.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857259

Analysis of the inhibitory effect of biguanides on glucose absorption: Inhibition of active sugar transport

25 September 2018

1 reference

12 December 2020

Effect of dimethylbiguanide on stomach emptying and on oral glucose tolerance

1 reference

12 December 2020

Isolation and use of liver cells

1 reference

12 December 2020

Enhanced glucose transport in response to inhibition of respiration in Clone 9 cells

1 reference

12 December 2020

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI30558

1 reference

release_pef6bsazfjbitg6xdqyzeps2ge

10 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pef6bsazfjbitg6xdqyzeps2ge

24 November 2022

mapped directly with Wikidata item

PMCID

1857259

1 reference

10 August 2017

1 reference