(Q34293073)

1 August 2017

title

The uroguanylin system and human disease (English)

1 reference

1 August 2017

Leong L Ng

4

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author name string

Hazim Rahbi

series ordinal

1

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1 August 2017

Hafid Narayan

series ordinal

2

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1 August 2017

Donald J L Jones

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

1 December 2012

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1 August 2017

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1 August 2017

volume

123

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1 August 2017

issue

12

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1 August 2017

page(s)

659-668

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Atrial natriuretic factor: a hormone produced by the heart

1 August 2017

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Guanylin: an endogenous activator of intestinal guanylate cyclase

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Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase

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Lymphoguanylin: cloning and characterization of a unique member of the guanylin peptide family

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Site-specific effects of dietary salt intake on guanylin and uroguanylin mRNA expression in rat intestine

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A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor

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Uroguanylin regulates net fluid secretion via the NHE2 isoform of the Na/H+ exchanger in an intestinal cellular model.

21 January 2018

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Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity

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Natriuretic and antikaliuretic effects of uroguanylin and prouroguanylin in the rat

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Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load

21 January 2018

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Circulating prouroguanylin is processed to its active natriuretic form exclusively within the renal tubules

21 January 2018

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Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics

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Uroguanylin, an intestinal natriuretic peptide, is delivered to the kidney as an unprocessed propeptide

21 January 2018

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The proximal convoluted tubule is a target for the uroguanylin-regulated natriuretic response.

21 January 2018

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The rat kidney contains high levels of prouroguanylin (the uroguanylin precursor) but does not express GC-C (the enteric uroguanylin receptor).

21 January 2018

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Uroguanylin: cloning of preprouroguanylin cDNA, mRNA expression in the intestine and heart and isolation of uroguanylin and prouroguanylin from plasma

21 January 2018

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Purification, cDNA sequence, and tissue distribution of rat uroguanylin

21 January 2018

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Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor

21 January 2018

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The natriuretic peptide uroguanylin elicits physiologic actions through 2 distinct topoisomers

21 January 2018

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Guanylin, uroguanylin, and heat-stable euterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G protein in human proximal tubule cells

21 January 2018

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Uroguanylin and guanylin regulate transport of mouse cortical collecting duct independent of guanylate cyclase C.

21 January 2018

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Cellular localization, membrane distribution, and possible function of guanylyl cyclases A and 1 in collecting ducts of rat.

21 January 2018

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The pendrin anion exchanger gene is transcriptionally regulated by uroguanylin: a novel enterorenal link

21 January 2018

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Transcriptional regulation of the pendrin gene

21 January 2018

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High-salt intake primes the rat kidney to respond to a subthreshold uroguanylin dose during ex vivo renal perfusion

21 January 2018

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Activation of a novel natriuretic endocrine system in humans with heart failure

21 January 2018

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Evaluation of novel biomarkers for the diagnosis of acute destabilised heart failure in patients with shortness of breath

21 January 2018

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21 January 2018

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21 January 2018

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The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.

21 January 2018

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Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity

21 January 2018

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Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation

21 January 2018

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Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

21 January 2018

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Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy

21 January 2018

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Can colorectal cancer be prevented or treated by oral hormone replacement therapy?

21 January 2018

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The prognostic effect of micrometastases in previously staged lymph node negative (N0) colorectal carcinoma: a meta-analysis.

21 January 2018

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Is occult lymph node disease in colorectal cancer patients clinically significant? A review of the relevant literature.

21 January 2018

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21 January 2018

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21 January 2018

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Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer

21 January 2018

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21 January 2018

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Identification of biologically active and inactive human uroguanylins in plasma and urine and their increases in renal insufficiency.

21 January 2018

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A uroguanylin-GUCY2C endocrine axis regulates feeding in mice

21 January 2018

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Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit

21 January 2018

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Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome

21 January 2018

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21 January 2018

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Effects of atrial natriuretic peptide on distal tubule function in humans

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/CS20120021

1 reference

1 August 2017

1 reference