(Q34294723)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

review article

1 reference

title

Transcription factors as drug targets: opportunities for therapeutic selectivity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

author name string

T R Butt

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

S K Karathanasis

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

publication date

1 January 1995

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

page(s)

319-336

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function

20 October 2019

cites work

1 reference

12 December 2020

Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily

1 reference

12 December 2020

ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.

1 reference

12 December 2020

A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways

1 reference

12 December 2020

Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells

1 reference

12 December 2020

High-density lipoprotein--the clinical implications of recent studies

1 reference

12 December 2020

Distinct classes of transcriptional activating domains function by different mechanisms

1 reference

12 December 2020

Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

1 reference

12 December 2020

Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation

1 reference

12 December 2020

The steroid and thyroid hormone receptor superfamily

1 reference

12 December 2020

Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link

1 reference

12 December 2020

P59, an hsp 90-binding protein. Cloning and sequencing of its cDNA and preparation of a peptide-directed polyclonal antibody

1 reference

12 December 2020

Activation and blockade of beta adrenoceptors in common cardiac disorders

1 reference

12 December 2020

Different cis-acting DNA elements control expression of the human apolipoprotein AI gene in different cell types

1 reference

12 December 2020

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen

1 reference

12 December 2020

Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.

1 reference

12 December 2020

Regulation of RNA polymerase II transcription

1 reference

12 December 2020

Alteration in the agonist/antagonist balance of antiestrogens by activation of protein kinase A signaling pathways in breast cancer cells: antiestrogen selectivity and promoter dependence

1 reference

12 December 2020

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone

1 reference

12 December 2020

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

12 December 2020

Apolipoprotein A-I metabolism in cholesteryl ester transfer protein transgenic mice. Insights into the mechanisms responsible for low plasma high density lipoprotein levels

1 reference

12 December 2020

Evolution of the nuclear receptor gene superfamily

1 reference

12 December 2020

Prediction of bone density from vitamin D receptor alleles

1 reference

12 December 2020

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1 reference

12 December 2020

[Recommendations for substitution with estrogens and progesterones in climacteric and in postmenopause. 8th Professional Meeting of the Zurich Discussion Group, November 1992]

1 reference

12 December 2020

Effects of immunosuppressants FK506 and rapamycin on the heterooligomeric form of the progesterone receptor

1 reference

12 December 2020

Cloning of the cDNA for the human beta 1-adrenergic receptor

1 reference

12 December 2020

Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein

1 reference

12 December 2020

A transcriptional hierarchy involved in mammalian cell-type specification

1 reference

12 December 2020

The mechanism by which the human apolipoprotein B gene reducer operates involves blocking of transcriptional activation by hepatocyte nuclear factor 3.

1 reference

12 December 2020

NF-AT-AP-1 and Rel-bZIP: hybrid vigor and binding under the influence

1 reference

12 December 2020

Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast

1 reference

12 December 2020

Activation of apolipoprotein AI gene transcription by the liver-enriched factor HNF-3.

1 reference

12 December 2020

Yeast transcription factors

1 reference

12 December 2020

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains

1 reference

12 December 2020

The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype

1 reference

12 December 2020

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

12 December 2020

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1 reference

12 December 2020

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1 reference

12 December 2020

Role of chromatin structure in the regulation of transcription by RNA polymerase II.

1 reference

12 December 2020

Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors

1 reference

12 December 2020

Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling

1 reference

12 December 2020

HNF1, a homeoprotein member of the hepatic transcription regulatory network

1 reference

12 December 2020

Transcriptional repression of apolipoprotein AI gene expression by orphan receptor ARP-1.

1 reference

12 December 2020

Human HDL cholesterol levels are determined by apoA-I fractional catabolic rate, which correlates inversely with estimates of HDL particle size. Effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distri

1 reference

12 December 2020

Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man

1 reference

12 December 2020

The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors

1 reference

12 December 2020

Immunosuppressants: tools to investigate the physiological role of cytokines

1 reference

12 December 2020

Plasma high density lipoproteins. Metabolism and relationship to atherogenesis

1 reference

12 December 2020

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo

1 reference

12 December 2020

Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI.

1 reference

12 December 2020

Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system

1 reference

12 December 2020

Heterodimeric receptor complexes determine 3,5,3'-triiodothyronine and retinoid signaling specificities

1 reference

12 December 2020

Orphan receptors: in search of a unifying hypothesis for activation

1 reference

12 December 2020

DNA inversion within the apolipoproteins AI/CIII/AIV-encoding gene cluster of certain patients with premature atherosclerosis

1 reference

12 December 2020

Nuclear receptor that identifies a novel retinoic acid response pathway

1 reference

12 December 2020

Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other

1 reference

12 December 2020

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

1 reference

12 December 2020

Transcriptional control in hepatocytes: a window on development

1 reference

12 December 2020

Rat liver c-erbA β1 thyroid hormone receptor is a constitutive activator in yeast (Saccharomyces cerevisiae): Essential role of domains D,E and F in hormone-independent transcription

1 reference

12 December 2020

The acidic activator GAL4-AH can stimulate polymerase II transcription by promoting assembly of a closed complex requiring TFIID and TFIIA

1 reference

12 December 2020

Differential induction of pS2 and cathepsin D mRNAs by structurally altered estrogens

1 reference

12 December 2020

Induction of Transforming Growth Factor β by the Antiestrogens Droloxifene, Tamoxifen, and Toremifene in MCF-7 Cells

1 reference

12 December 2020

Prevention and treatment of osteoporosis with hormone replacement therapy.

1 reference

12 December 2020

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions

1 reference

12 December 2020

Human estrogen receptor mutants with altered estrogen and antiestrogen ligand discrimination

1 reference

12 December 2020

Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice

1 reference

12 December 2020

The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly

1 reference

12 December 2020

Endocrine pharmacology of antiestrogens as antitumor agents

1 reference

12 December 2020

Gene regulation in rodent hepatocytes during development, differentiation and disease

1 reference

12 December 2020

Plasma cholesteryl ester transfer protein

1 reference

12 December 2020

Effects of estradiol-17 beta analogues on activation of estrogen response element regulated chloramphenicol acetyltransferase expression

1 reference

12 December 2020

Novel steroidal pure antiestrogens

1 reference

12 December 2020

Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc

1 reference

12 December 2020

Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV genes

1 reference

12 December 2020

A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor

1 reference

12 December 2020

COUP transcription factor is a member of the steroid receptor superfamily

1 reference

12 December 2020

Differential DNA-binding abilites of estrogen receptor occupied with two classes of antiestrogens: studies using human estrogen receptor overexpressed in mammalian cells

1 reference

12 December 2020

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head

1 reference

12 December 2020

New immunosuppressive agents.

1 reference

12 December 2020

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

1 reference

12 December 2020

Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins

1 reference

12 December 2020

Distribution of apolipoprotein A-I, C-II, C-III, and E mRNA in fetal human tissues. Time-dependent induction of apolipoprotein E mRNA by cultures of human monocyte-macrophages

1 reference

12 December 2020

Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization

1 reference

12 December 2020

Interaction between a transcriptional activator and transcription factor IIB in vivo.

1 reference

12 December 2020

Pharmacology of cyclosporine (sandimmune). I. Introduction

1 reference

12 December 2020

HNF-3 beta is essential for node and notochord formation in mouse development

1 reference

12 December 2020

Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit

1 reference

12 December 2020

Evolutionary distinct mechanisms regulate apolipoprotein A-I gene expression: differences between avian and mammalian apoA-I gene transcription control regions

1 reference

12 December 2020

Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice

1 reference

12 December 2020

The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

1 reference

12 December 2020

Structure, evolution, and tissue-specific synthesis of human apolipoprotein AIV

1 reference

12 December 2020

Repression by ARP-1 Sensitizes Apolipoprotein A1 Gene Responsiveness to RXRα and Retinoic Acid

1 reference

12 December 2020

Nuclear factor of activated T cells contains Fos and Jun.

1 reference

12 December 2020

Reduced high density lipoprotein cholesterol in human cholesteryl ester transfer protein transgenic mice

1 reference

12 December 2020

Prevention of spinal osteoporosis in oophorectomised women

1 reference

12 December 2020

International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification.

1 reference

12 December 2020

Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements

1 reference

12 December 2020

Cytokines and estrogen in bone: anti-osteoporotic effects

1 reference

12 December 2020

Synergistic interactions between transcription factors control expression of the apolipoprotein AI gene in liver cells

1 reference

12 December 2020

High levels of human apolipoprotein A-I in transgenic mice result in increased plasma levels of small high density lipoprotein (HDL) particles comparable to human HDL3

1 reference

12 December 2020

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1 reference

12 December 2020

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens

1 reference

12 December 2020

Signal transduction events leading to T-cell lymphokine gene expression

1 reference

12 December 2020

Steroid and related receptors

1 reference

12 December 2020

Human estrogen receptor regulation in a yeast model system and studies on receptor agonists and antagonists

1 reference

12 December 2020

Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes

1 reference

12 December 2020

Subtypes of alpha 1- and alpha 2-adrenergic receptors

1 reference

12 December 2020

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1 reference

12 December 2020

Intestinal expression of the human apoA-I gene in transgenic mice is controlled by a DNA region 3' to the gene in the promoter of the adjacent convergently transcribed apoC-III gene

1 reference

12 December 2020

The metabolism of high-density lipoproteins

1 reference

12 December 2020

The mechanism of action of cyclosporin A and FK506

1 reference

12 December 2020

Clinical trials with the topoisomerase I inhibitors

1 reference

12 December 2020

Modulation of transforming growth factor-beta production in normal human osteoblast-like cells by 17 beta-estradiol and parathyroid hormone

1 reference

12 December 2020

NF-AT components define a family of transcription factors targeted in T-cell activation

1 reference

12 December 2020

DNA topoisomerase I is involved in both repression and activation of transcription

1 reference

12 December 2020

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

1 reference

12 December 2020

Activation of RNA polymerase II transcription by the specific DNA-binding protein LSF. Increased rate of binding of the basal promoter factor TFIIB

1 reference

12 December 2020

Modeling eukaryotic transcriptional activation

1 reference

12 December 2020

NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs

1 reference

12 December 2020

Characterization of a negative retinoic acid response element in the murine Oct4 promoter

1 reference

12 December 2020

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7549464%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

PubMed publication ID

7549464

1 reference