(Q34299310)

English

Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease.

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Alzheimer's disease

0 references

0 references

1 reference

based on heuristic

inferred from title

cerebral amyloid angiopathy

1 reference

based on heuristic

inferred from title

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Terry L Lewis

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Dongfeng Cao

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Hailin Lu

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Robert A Mans

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Yan Ru Su

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Lisa Jungbauer

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

MacRae F Linton

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Sergio Fazio

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

language of work or name

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publication date

16 September 2010

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Europe PubMed Central

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14 February 2020

Journal of Biological Chemistry

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

285

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

47

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

36958-36968

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Mechanisms underlying inflammation in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Neuroinflammation – An Early Event in Both the History and Pathogenesis of Alzheimer’s Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Obesity and Alzheimer's disease: a link between body weight and cognitive function in old age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Physical activity, diet, and risk of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

The roles of PON1 and PON2 in cardiovascular disease and innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Cardiovascular risk factors and dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife: the Whitehall II study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Lentiviral transduction of apoAI into hematopoietic progenitor cells and macrophages: applications to cell therapy of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

The actions of BDNF on dendritic spine density and morphology in organotypic slice cultures depend on the presence of serum in culture media

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Molecular regulation of macrophage reverse cholesterol transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Invited commentary: lipoproteins and dementia - is it the apolipoprotein A-I?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

APOA1 polymorphism influences risk for early-onset nonfamiliar AD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

The double jeopardy of HDL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

HDL as a target in the treatment of atherosclerotic cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Antiinflammatory properties of HDL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Relation of plasma lipids to Alzheimer disease and vascular dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Association of aortic atherosclerosis with cerebral beta-amyloidosis and learning deficits in a mouse model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Characterization of four lipoprotein classes in human cerebrospinal fluid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Paraoxonase and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Cholesterol metabolism in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

The human astrocytoma cell line U373MG produces monocyte chemotactic protein (MCP)-1 upon stimulation with beta-amyloid protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

High density associated enzymes: their role in vascular biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978624

6 July 2018

2010 Alzheimer's disease facts and figures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Increased cholesterol efflux in apolipoprotein AI (ApoAI)-producing macrophages as a mechanism for reduced atherosclerosis in ApoAI((-/-)) mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Macrophage apolipoprotein A-I expression protects against atherosclerosis in ApoE-deficient mice and up-regulates ABC transporters.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

An apolipoprotein A-I gene promoter polymorphism associated with cognitive decline, but not with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

The relation between apolipoprotein A-I and dementia: the Honolulu-Asia aging study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Simvastatin enhances learning and memory independent of amyloid load in mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Lack of LDL receptor aggravates learning deficits and amyloid deposits in Alzheimer transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Double belt structure of discoidal high density lipoproteins: molecular basis for size heterogeneity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Cerebrospinal fluid apo E and apo A-I concentrations in early- and late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Cholesterol and neuropathologic markers of AD: a population-based autopsy study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Plasma HDL levels highly correlate with cognitive function in exceptional longevity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

A genotype of exceptional longevity is associated with preservation of cognitive function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

HDL: close to our memories?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.127829

21 January 2018

Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice induces hyperlipidemia but reduces atherogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum Paraoxonase Activity, Concentration, and Phenotype Distribution in Diabetes Mellitus and Its Relationship to Serum Lipids and Lipoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked decrease of plasma apolipoprotein AI and AII in Japanese patients with late-onset non-familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A-I in the human artery wall with the progression of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's amyloid beta interaction with normal human plasma high density lipoprotein: association with apolipoprotein and lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.127829

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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