(Q34300200)

1 August 2017

title

The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity (English)

1 reference

1 August 2017

author

Oraphin Chantarasriwong

object named as

Oraphin Chantarasriwong

3

0 references

John Yu

object named as

John Yu

9

0 references

Alice L Yu

object named as

Alice L Yu

8

0 references

author name string

Ayse Batova

1

1 reference

1 August 2017

Diego Altomare

2

1 reference

1 August 2017

Kari L Ohlsen

4

1 reference

1 August 2017

Kim E Creek

5

1 reference

1 August 2017

You-Chin Lin

6

1 reference

1 August 2017

Amy Messersmith

7

1 reference

1 August 2017

Emmanuel A Theodorakis

10

1 reference

1 August 2017

publication date

29 September 2010

1 reference

Molecular Cancer Therapeutics

1 August 2017

published in

1 reference

1 August 2017

volume

9

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1 August 2017

issue

11

1 reference

1 August 2017

page(s)

2869-2878

1 reference

Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway

1 August 2017

cites work

1 reference

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6 July 2018

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Evaluation of the pharmacophoric motif of the caged Garcinia xanthones

6 July 2018

1 reference

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Housekeeping genes in prostate tumorigenesis

6 July 2018

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Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Mitochondria as targets for cancer therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Elesclomol induces cancer cell apoptosis through oxidative stress

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Gambogic acid induced tumor cell apoptosis by T lymphocyte activation in H22 transplanted mice

6 July 2018

1 reference

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Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins

6 July 2018

1 reference

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DNA damage repair and response proteins as targets for cancer therapy

6 July 2018

1 reference

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Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo study

6 July 2018

1 reference

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A systems biology approach for pathway level analysis

6 July 2018

1 reference

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Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Structure and function: heat shock proteins and adaptive immunity.

6 July 2018

1 reference

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Differential regulation of human NK cell-mediated cytotoxicity by the tyrosine kinase Itk.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Synthesis and evaluation of caged Garcinia xanthones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Role of MAP kinase-dependent apoptotic pathway in innate immune responses and viral infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Repression of telomerase reverse transcriptase mRNA and hTERT promoter by gambogic acid in human gastric carcinoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Linking tumor cell cytotoxicity to mechanism of drug action: an integrated analysis of gene expression, small-molecule screening and structural databases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Effects of WNT/beta-catenin pathway activation on signaling through T-cell factor and androgen receptor in prostate cancer cell lines.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

CD69 is an immunoregulatory molecule induced following activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Unified synthesis of caged Garcinia natural products based on a site-selective Claisen/Diels-Alder/Claisen rearrangement

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Lymphoid enhancer factor/T cell factor expression in colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Antioxidants and oxidants regulated signal transduction pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Identification of c-MYC as a target of the APC pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Cytotoxic xanthones from Garcinia hanburyi

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

Expression of lymphoid enhancer factor/T-cell factor proteins in colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978789

The comet assay: a method to measure DNA damage in individual cells

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20881270

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-10-0517

1 reference

1 August 2017

1 reference

1 August 2017

1 reference