(Q34304960)

1 August 2017

title

Orai1 interacts with STIM1 and mediates capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells (English)

1 reference

1 August 2017

9

0 references

Cherie A. Singer

4

Cherie A Singer

0 references

Honglin Tian

7

0 references

Maria L. Valencik

8

Maria Valencik

0 references

Lih Chyuan Ng

1

Lih Chyuan Ng

0 references

Judith A. Airey

3

Judith A Airey

0 references

author name string

Deepa Ramduny

2

1 reference

1 August 2017

Xiao-Ming Shen

6

1 reference

1 August 2017

Phillip S. Keller

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739625

23 June 2024

Maria Valencik

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739625

23 June 2024

language of work or name

1 reference

25 August 2010

1 reference

full work available at URL

1 August 2017

https://europepmc.org/articles/pmc2980318

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739625

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20739625/?tool=EBI

23 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739625

http://intl-ajpcell.physiology.org/cgi/content/abstract/299/5/C1079

23 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739625

https://europepmc.org/articles/PMC2980318

23 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739625

https://doi.org/10.1152/ajpcell.00548.2009

23 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739625

https://journals.physiology.org/doi/pdf/10.1152/ajpcell.00548.2009

23 June 2024

1 reference

10.1152/AJPCELL.00548.2009

DOI

https://api.crossref.org/works/10.1152/AJPCELL.00548.2009

American Journal of Physiology - Cell Physiology

23 June 2024

published in

1 reference

1 August 2017

volume

299

1 reference

1 August 2017

issue

5

1 reference

1 August 2017

page(s)

C1079-90

1 reference

Orai1, a critical component of store-operated Ca2+ entry, is functionally associated with Na+/Ca2+ exchanger and plasma membrane Ca2+ pump in proliferating human arterial myocytes

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Knockdown of stromal interaction molecule 1 attenuates store-operated Ca2+ entry and Ca2+ responses to acute hypoxia in pulmonary arterial smooth muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Location and function of STIM1 in the activation of Ca2+ entry signals.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Ca2+ handling is altered when arterial myocytes progress from a contractile to a proliferative phenotype in culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Differences in STIM1 and TRPC expression in proximal and distal pulmonary arterial smooth muscle are associated with differences in Ca2+ responses to hypoxia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Store-operated calcium entry in vascular smooth muscle.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Multiple activation mechanisms of store-operated TRPC channels in smooth muscle cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Role of STIM and Orai proteins in the store-operated calcium signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Some assembly required: constructing the elementary units of store-operated Ca2+ entry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Orai proteins interact with TRPC channels and confer responsiveness to store depletion.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Involvement of transient receptor potential canonical 1 (TRPC1) in angiotensin II-induced vascular smooth muscle cell hypertrophy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Emerging perspectives in store-operated Ca2+ entry: roles of Orai, Stim and TRP.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Orai1 is an essential pore subunit of the CRAC channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Orai1 and STIM reconstitute store-operated calcium channel function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

TRP channels: an overview

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

STIM1, an essential and conserved component of store-operated Ca2+ channel function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Store-operated calcium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Store-operated Ca2+-permeable non-selective cation channels in smooth muscle cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins

6 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

6 July 2018

https://pubmed.ncbi.nlm.nih.gov/20739625

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

STIM1: a novel phosphoprotein located at the cell surface.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Cell proliferation is associated with enhanced capacitative Ca(2+) entry in human arterial myocytes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

A new generation of Ca2+ indicators with greatly improved fluorescence properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980318

Activation of store-operated channels by noradrenaline via protein kinase C in rabbit portal vein myocytes

6 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca(2+) store in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Overexpression of TRPC1 enhances pulmonary vasoconstriction induced by capacitative Ca2+ entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Interactions, functions, and independence of plasma membrane STIM1 and TRPC1 in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Store-operated channels mediate Ca(2+) influx and contraction in rat pulmonary artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Cell culture alters Ca2+ entry pathways activated by store-depletion or hypoxia in canine pulmonary arterial smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

TRPC1 and STIM1 mediate capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Angiotensin II activates two cation conductances with distinct TRPC1 and TRPC6 channel properties in rabbit mesenteric artery myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Inhibition of endogenous TRP1 decreases capacitative Ca2+ entry and attenuates pulmonary artery smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Properties of a native cation channel activated by Ca2+ store depletion in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Capacitative calcium entry and TRPC channel proteins are expressed in rat distal pulmonary arterial smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Visualization and Manipulation of Plasma Membrane-Endoplasmic Reticulum Contact Sites Indicates the Presence of Additional Molecular Components within the STIM1-Orai1 Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2009

Functional role of stromal interaction molecule 1 (STIM1) in vascular smooth muscle cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739625

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential expression and alternative splicing of TRP channel genes in smooth muscles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739625

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPCELL.00548.2009

1 reference

1 August 2017

1 reference

1 August 2017

1 reference