(Q34306286)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22703232%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer (English)

1 reference

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5 February 2020

1 reference

4

1 reference

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5 February 2020

Oddrun Gudbrandsen

6

1 reference

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5 February 2020

8

Gunnar Mellgren

1 reference

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5 February 2020

author name string

Line L Haugan Moi

1

1 reference

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5 February 2020

Marianne Hauglid Flågeng

2

1 reference

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5 February 2020

Jennifer Gjerde

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22703232%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Therese Halvorsen Røst

5

1 reference

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5 February 2020

Ernst A Lien

7

1 reference

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5 February 2020

language of work or name

English

0 references

publication date

15 June 2012

1 reference

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5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22703232%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

12

1 reference

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5 February 2020

page(s)

247

1 reference

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https://scigraph.springernature.com/pub.10.1186/1471-2407-12-247

5 February 2020

exact match

0 references

cites work

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Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases?

6 July 2018

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Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors

6 July 2018

1 reference

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AIB1 is required for the acquisition of epithelial growth factor receptor-mediated tamoxifen resistance in breast cancer cells

6 July 2018

1 reference

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Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence

6 July 2018

1 reference

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Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation

6 July 2018

1 reference

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Pharmacogenetics and breast cancer endocrine therapy: CYP2D6 as a predictive factor for tamoxifen metabolism and drug response?

6 July 2018

1 reference

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Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen

6 July 2018

1 reference

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Tamoxifen impairs both longitudinal and cortical bone growth in young male rats

6 July 2018

1 reference

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Selective estrogen-receptor modulators and antihormonal resistance in breast cancer

6 July 2018

1 reference

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Tamoxifen-induced ER-alpha-SRC-3 interaction in HER2 positive human breast cancer; a possible mechanism for ER isoform specific recurrence.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer

6 July 2018

1 reference

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

6 July 2018

1 reference

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Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer

6 July 2018

1 reference

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Expression of SRC-1, AIB1, and PEA3 in HER2 mediated endocrine resistant breast cancer; a predictive role for SRC-1.

6 July 2018

1 reference

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Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer

6 July 2018

1 reference

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Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells

6 July 2018

1 reference

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Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase

6 July 2018

1 reference

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Expression of the nuclear coactivator AIB1 in normal and malignant breast tissue.

6 July 2018

1 reference

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Estrogens and cell-cycle regulation in breast cancer

6 July 2018

1 reference

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Overexpression of the steroid receptor coactivator AIB1 in breast cancer correlates with the absence of estrogen and progesterone receptors and positivity for p53 and HER2/neu.

6 July 2018

1 reference

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Altered expression of estrogen receptor coregulators during human breast tumorigenesis

6 July 2018

1 reference

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8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein

6 July 2018

1 reference

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The ErbB signaling network: receptor heterodimerization in development and cancer

6 July 2018

1 reference

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AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

6 July 2018

1 reference

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Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells

6 July 2018

1 reference

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Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer

6 July 2018

1 reference

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Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

6 July 2018

1 reference

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AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

6 July 2018

1 reference

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ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu

6 July 2018

1 reference

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HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Emergence of MCF-7 cells overexpressing a transfected epidermal growth factor receptor (EGFR) under estrogen-depleted conditions: evidence for a role of EGFR in breast cancer growth and progression.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Oestrogen and epidermal growth factor down-regulate erbB-2 oncogene protein expression in breast cancer cells by different mechanisms.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Pharmacodynamic and biological effects of anti-estrogens in different models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Expression of Sex Steroid Receptors and their Co-Factors in Normal and Malignant Breast Tissue: AIB1 is a Carcinoma-Specific Co-Activator

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Coactivators PGC-1beta and SRC-1 interact functionally to promote the agonist activity of the selective estrogen receptor modulator tamoxifen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Identification and quantification of tamoxifen and four metabolites in serum by liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Tamoxifen administration and metabolism in nude mice and nude rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Co-Expression of ErbB-Family Members in Human Breast Cancer: Her-2/neu is the Preferred Dimerization Candidate in Nodal-positive Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Induction of hepatic drug-metabolising enzymes and tamoxifen metabolite profile in relation to administration route during low-dose treatment in nude rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Tamoxifen and metabolite concentrations in serum and breast cancer tissue during three dose regimens in a randomized preoperative trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-247

Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3420308

Active signaling by Neu in transgenic mice

28 October 2018

1 reference

12 December 2020

Inhibition of c-erbB-2 oncogene expression by estrogens in human breast cancer cells

1 reference

12 December 2020

Distribution of 4-hydroxy-N-desmethyltamoxifen and other tamoxifen metabolites in human biological fluids during tamoxifen treatment

1 reference

12 December 2020

Hormonal modulation of HER-2/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell lines

1 reference

12 December 2020

Identification of 4-hydroxy-N-desmethyltamoxifen as a metabolite of tamoxifen in human bile

1 reference

12 December 2020

Downregulation of erbB3 abrogates erbB2-mediated tamoxifen resistance in breast cancer cells

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-12-247

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22703232%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22703232%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22703232%20AND%20SRC:MED&resulttype=core&format=json