(Q34308827)

1 August 2017

1 reference

title

Apoptosis and dependence receptors: a molecular basis for cellular addiction (English)

1 reference

extrinsic apoptotic signaling pathway in absence of ligand

1 August 2017

main subject

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0097192

signal transduction in absence of ligand

1 reference

Gene Ontology release 2020-05-02

1 reference

Dale E Bredesen

1

1 reference

1 August 2017

Patrick Mehlen

series ordinal

2

1 reference

1 August 2017

Shahrooz Rabizadeh

series ordinal

3

1 reference

1 August 2017

publication date

1 April 2004

1 reference

1 August 2017

published in

Physiological Reviews

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1 August 2017

volume

84

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1 August 2017

issue

2

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1 August 2017

page(s)

411-430

1 reference

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

1 August 2017

cites work

1 reference

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p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

21 January 2018

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Targeting the prostate for destruction through a vascular address

21 January 2018

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Identification of Shc docking site on Ret tyrosine kinase

21 January 2018

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TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret.

21 January 2018

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The GDNF family ligands and receptors - implications for neural development

21 January 2018

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The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

p75NTR and apoptosis: Trk-dependent and Trk-independent effects

21 January 2018

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p75NTR and the concept of cellular dependence: seeing how the other half die.

21 January 2018

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

21 January 2018

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GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney

21 January 2018

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Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

21 January 2018

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The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death

21 January 2018

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Gene transfer and molecular cloning of the human NGF receptor.

21 January 2018

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The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells

21 January 2018

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DCC: linking tumor suppressor genes and altered cell surface interactions in cancer?

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

cDCC (chicken homologue to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Developmental cell death: morphological diversity and multiple mechanisms

21 January 2018

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Axon guidance to and from choice points.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Chopper, a New Death Domain of the p75 Neurotrophin Receptor That Mediates Rapid Neuronal Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Mutations of the RET proto-oncogene in Hirschsprung's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Anti-cancer activity of targeted pro-apoptotic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Caspase 7 can cleave tumor necrosis factor receptor-I (p60) at a non-consensus motif, in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Identification of a chromosome 18q gene that is altered in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

PLAIDD, a type II death domain protein that interacts with p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Disruption of epithelial cell-matrix interactions induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Caspase cleavage of members of the amyloid precursor family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The DCC gene product in cellular differentiation and colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Suppressed tumorigenicity of human endometrial cancer cells by the restored expression of the DCC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

A comparison of the cytoplasmic domains of the Fas receptor and the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Inherited Neurodegenerative Disorders Caused by CAG/Polyglutamine Tract Expansions: Symposium Introduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Regulation of cell survival by secreted proneurotrophins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Mediation of the DCC apoptotic signal by DIP13 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Programmed cell death—II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The protooncogene bcl-2 inhibits apoptosis in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Role of the dependence receptor DCC in colorectal cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

An induced proximity model for caspase-8 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Caspases: killer proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Signaling through scaffold, anchoring, and adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Various mechanisms cause RET-mediated signaling defects in Hirschsprung's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Mutant sensory cilia in the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Discussion point. The case for floor plate induction by the notochord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Getting hydrophilic compounds into cells: lessons from homeopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Is p75NGFR involved in developmental neural cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Induction of apoptosis by the low-affinity NGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Neurotrophin dependence mediated by p75NTR: contrast between rescue by BDNF and NGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Gene transfer and molecular cloning of the rat nerve growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

21 January 2018

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Caspases: intracellular signaling by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Controlling Signal Transduction with Synthetic Ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

An alternative, nonapoptotic form of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

ret transforming gene encodes a fusion protein homologous to tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Cadherin cell adhesion receptors as a morphogenetic regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

p53RDL1 regulates p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The molecular biology of axon guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Autoproteolytic activation of pro-caspases by oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Extension of long leading processes and neuronal migration in the mammalian brain directed by the chemoattractant netrin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

Induction of cell death by endogenous nerve growth factor through its p75 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00027.2003

10.1152/PHYSREV.00027.2003

21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference