(Q34309465)

1 August 2017

Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function (English)

1 reference

1 August 2017

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0 references

1 reference

1 reference

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Anusha Jayaraman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Daniella Lent-Schochet

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

publication date

16 September 2014

1 reference

Journal of Neuroinflammation

1 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

162

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

2 June 2020

copyright license

start time

16 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s12974-014-0162-y

0 references

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17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain

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6 July 2018

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Caspase activation contributes to astrogliosis

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Synapse loss induced by interleukin-1β requires pre- and post-synaptic mechanisms

6 July 2018

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Testosterone supplementation in male obese Zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure

6 July 2018

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The hormonal pathway to cognitive impairment in older men.

6 July 2018

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Obesity and type 2 diabetes: which patients are at risk?

6 July 2018

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Dihydrotestosterone inhibits interleukin-1α or tumor necrosis factor α-induced proinflammatory cytokine production via androgen receptor-dependent inhibition of nuclear factor-κB activation in rheumatoid fibroblast-like synovial cell line

6 July 2018

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Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-α

6 July 2018

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Testosterone levels and cognition in elderly men: a review.

6 July 2018

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Functional relationship between obesity and male reproduction: from humans to animal models

6 July 2018

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Type 2 diabetes as an inflammatory disease

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Testosterone and metabolic syndrome: a meta-analysis study

6 July 2018

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Testosterone and type 2 diabetes

6 July 2018

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Different nitrosative-induced microtubular modifications and testosterone neuroprotective effects on high-D-glucose-exposed neuroblastoma and glioma cells.

6 July 2018

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Testosterone deficiency, insulin resistance and the metabolic syndrome

6 July 2018

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Diabetic painful and insensate neuropathy: pathogenesis and potential treatments

6 July 2018

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Neuroprotective effects of a ligand of translocator protein-18 kDa (Ro5-4864) in experimental diabetic neuropathy.

6 July 2018

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NFkappaB-mediated metabolic inflammation in peripheral tissues versus central nervous system

6 July 2018

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Testosterone and dihydrotestosterone differentially improve cognition in aged female mice

6 July 2018

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The role of testosterone in the metabolic syndrome: a review

6 July 2018

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Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease

6 July 2018

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Contribution of vascular risk factors to the progression in Alzheimer disease

6 July 2018

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6 July 2018

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Nociceptors are interleukin-1beta sensors

6 July 2018

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Testosterone in obesity, metabolic syndrome and type 2 diabetes

6 July 2018

1 reference

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Testosterone concentration in young patients with diabetes

6 July 2018

1 reference

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Inverse association of testosterone and the metabolic syndrome in men is consistent across race and ethnic groups

6 July 2018

1 reference

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Androgen deficiency as a predictor of metabolic syndrome in aging men: an opportunity for intervention?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Androgen deprivation therapy in prostate cancer and metabolic risk for atherosclerosis

6 July 2018

1 reference

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Inflammation and metabolic disorders

6 July 2018

1 reference

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Effects of testosterone supplementation on whole body and regional fat mass and distribution in human immunodeficiency virus-infected men with abdominal obesity

6 July 2018

1 reference

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Testosterone and cognitive function: current clinical evidence of a relationship

6 July 2018

1 reference

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Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapy

6 July 2018

1 reference

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A work in progress: the metabolic syndrome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

The role of androgens in cognition and brain aging in men.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Androgens activate mitogen-activated protein kinase signaling: role in neuroprotection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

The decline of androgen levels in elderly men and its clinical and therapeutic implications

6 July 2018

1 reference

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Immune and glial cell factors as pain mediators and modulators

6 July 2018

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Gene expression patterns in in vivo normal adult astrocytes compared with cultured neonatal and normal adult astrocytes

6 July 2018

1 reference

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Free testosterone and risk for Alzheimer disease in older men

6 July 2018

1 reference

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Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency

6 July 2018

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Testosterone attenuates beta-amyloid toxicity in cultured hippocampal neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

The action of steroid hormones on peripheral myelin proteins: a possible new tool for the rebuilding of myelin?

6 July 2018

1 reference

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Brain aromatase is neuroprotective

6 July 2018

1 reference

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6 July 2018

1 reference

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Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Estrogen modulates neuronal Bcl-xL expression and beta-amyloid-induced apoptosis: relevance to Alzheimer's disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

The effect of age and testosterone on the expression of glial fibrillary acidic protein in the rat cerebellum

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Inflammatory properties of recombinant tumor necrosis factor in rabbit skin in vivo

6 July 2018

1 reference

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Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease.

6 July 2018

1 reference

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Androgens increase spine synapse density in the CA1 hippocampal subfield of ovariectomized female rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Low androgenization index in elderly women and elderly men with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

21 January 2018

1 reference

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Testosterone levels in males with type 2 diabetes and their relationship with cardiovascular risk factors and cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

The metabolic syndrome, inflammation, and risk of cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: correlations with bioavailable testosterone and visceral adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Association between Relative Hypogonadism and Metabolic Syndrome in Newly Diagnosed Adult Male Patients with Impaired Glucose Tolerance or Type 2 Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Low testosterone levels are common and associated with insulin resistance in men with diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Effects of androgen deprivation on glycaemic control and on cardiovascular biochemical risk factors in men with advanced prostate cancer with diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Low levels of sex hormone-binding globulin and testosterone predict the development of non-insulin-dependent diabetes mellitus in men. MRFIT Research Group. Multiple Risk Factor Intervention Trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Testosterone and obesity in men under the age of 40 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Effects of androgen therapy on adipose tissue and metabolism in older men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Interferon-gamma but not TNF alpha promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Interleukin-1β inhibits the differentiation of hippocampal neural precursor cells into serotonergic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Erythrocyte Na(+)-K(+)-ATPase activity, metabolic control, and neuropathy in IDDM patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Metabolic syndrome and amnestic mild cognitive impairment: Singapore Longitudinal Ageing Study-2 findings.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Testosterone and gonadotropin levels in men with dementia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Gonadal hormones affect spine synaptic density in the CA1 hippocampal subfield of male rats.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Serum total testosterone is lower in men with Alzheimer's disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190446

Testosterone derivatives are neuroprotective agents in experimental diabetic neuropathy

28 October 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0162-Y

Induction of LH hypersecretion in cyclic rats during the afternoon of oestrus by oestrogen in conjunction with progesterone antagonism or opioidergic blockade

21 January 2018

1 reference

12 December 2020

Effect of immunization with lutropin-receptor on the ovarian function of rabbits

1 reference

12 December 2020

P0 phosphorylation in nerves from normal and diabetic rats: role of protein kinase C and turnover of phosphate groups

1 reference

12 December 2020

Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study

1 reference

12 December 2020

1 reference

12 December 2020

What to do about the metabolic syndrome?

1 reference

12 December 2020

Decrease of nerve Na+,K(+)-ATPase activity in the pathogenesis of human diabetic neuropathy

1 reference

12 December 2020

ATPase activity defects in alloxan-induced diabetic sciatic nerve recovered by ganglioside treatment

1 reference

12 December 2020

The effect of substance P1-7 amide on nociceptive threshold in diabetic mice

1 reference

12 December 2020

Hyperalgesia in spontaneous and experimental animal models of diabetic neuropathy

1 reference

12 December 2020

Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer

1 reference

12 December 2020

10.1186/S12974-014-0162-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25224590%20AND%20SRC:MED&resulttype=core&format=json