(Q34313553)

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The multi-structural feature of the multidrug resistance gene product P-glycoprotein: implications for its mechanism of action (hypothesis).

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scholarly article

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Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

The multi-structural feature of the multidrug resistance gene product P-glycoprotein: implications for its mechanism of action (hypothesis). (English)

1 reference

Europe PubMed Central

1 August 2017

multiple drug resistance

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based on heuristic

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author name string

Zhang JT

1

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Europe PubMed Central

1 August 2017

language of work or name

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based on heuristic

inferred from title

publication date

1 April 2001

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Europe PubMed Central

1 August 2017

Molecular Membrane Biology

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Europe PubMed Central

1 August 2017

18

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Europe PubMed Central

1 August 2017

145-152

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Europe PubMed Central

1 August 2017

2

1 reference

Europe PubMed Central

1 August 2017

Multidrug resistance protein (Mdr)-alkaline phosphatase hybrids in Escherichia coli suggest a major revision in the topology of the C-terminal half of Mdr.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Intracellular protein topogenesis

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

ATP-dependent transport systems in bacteria and humans: relevance to cystic fibrosis and multidrug resistance

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Predicting the orientation of eukaryotic membrane-spanning proteins

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Proximity of the nucleotide binding domains of the P-glycoprotein multidrug transporter to the membrane surface: a resonance energy transfer study.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Membrane topology of a cysteine-less mutant of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

The glycosylation and orientation in the membrane of the third cytoplasmic loop of human P-glycoprotein is affected by mutations and substrates.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Identification of members of the P-glycoprotein multigene family

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Lower electrical membrane potential and altered pHi homeostasis in multidrug-resistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Epitope mapping of the monoclonal antibody MM12.10 to external MDR1 P-glycoprotein domain by synthetic peptide scanning and phage display technologies.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

A general pattern for substrate recognition by P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Characterization and epitope mapping of several new anti-P-glycoprotein monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Dissection of drug-binding-induced conformational changes in P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Conformational changes of P-glycoprotein by nucleotide binding

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Membrane orientation of transmembrane segments 11 and 12 of MDR- and non-MDR-associated P-glycoproteins.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Dissection of de novo membrane insertion activities of internal transmembrane segments of ATP-binding-cassette transporters: toward understanding topological rules for membrane assembly of polytopic membrane proteins

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Topological determinants of internal transmembrane segments in P-glycoprotein sequences.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Topological folding and proteolysis profile of P-glycoprotein in membranes of multidrug-resistant cells: implications for the drug-transport mechanism.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Insertion of a multispanning membrane protein occurs sequentially and requires only one signal sequence

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Identification of Residues in the Drug-binding Site of Human P-glycoprotein Using a Thiol-reactive Substrate

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Identification of Residues in the Drug-binding Domain of Human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Biogenesis of Polytopic Membrane Proteins: Membrane Segments Assemble within Translocation Channels prior to Membrane Integration

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

P-glycoprotein epitope mapping. I. Identification of a linear human-specific epitope in the fourth loop of the P-glycoprotein extracellular domain by MM4.17 murine monoclonal antibody to human multi-drug-resistant cells.

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Localization of the iodomycin binding site in hamster P-glycoprotein

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Mechanism involved in generating the carboxyl-terminal half topology of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Membrane orientation of carboxyl-terminal half P-glycoprotein: topogenesis of transmembrane segments

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Membrane topology of P-glycoprotein as determined by epitope insertion: transmembrane organization of the N-terminal domain of mdr3

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Fluorescence studies on the nucleotide binding domains of the P-glycoprotein multidrug transporter

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Role of ribosomes in reinitiation of membrane insertion of internal transmembrane segments in a polytopic membrane protein

1 reference

https://api.crossref.org/works/10.1080%2F09687680110048831

21 January 2018

Identifiers

10.1080/09687680110048831

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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