(Q34313816)

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Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure-activity relationship (QSAR) of diverse heterocyclic scaffolds

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure-activity relationship (QSAR) of diverse heterocyclic scaffolds (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

toll-like receptor

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quantitative structure-activity relationship

1 reference

based on heuristic

inferred from title

Deepak B Salunke

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25192394%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

3

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1 June 2020

Ward H. Thompson

10

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1 June 2020

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Euna Yoo

1

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1 June 2020

Xiaoqiang Guo

4

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1 June 2020

Alex C D Salyer

5

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1 June 2020

Alec R Hermanson

6

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1 June 2020

Manoj Kumar

7

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1 June 2020

Subbalakshmi S Malladi

8

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1 June 2020

Rajalakshmi Balakrishna

9

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1 June 2020

Hiromi Tanji

11

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1 June 2020

Umeharu Ohto

12

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1 June 2020

Toshiyuki Shimizu

13

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1 June 2020

Sunil A David

14

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1 June 2020

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17 September 2014

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1 August 2017

Journal of Medicinal Chemistry

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1 June 2020

57

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1 June 2020

19

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1 June 2020

7955-7970

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25192394%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Structure-Based Design of Novel Human Toll-like Receptor 8 Agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Exquisite selectivity for human toll-like receptor 8 in substituted furo[2,3-c]quinolines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Design and development of stable, water-soluble, human Toll-like receptor 2 specific monoacyl lipopeptides as candidate vaccine adjuvants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo[4,5-c]quinolines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Structure-activity relationships in human Toll-like receptor 8-active 2,3-diamino-furo[2,3-c]pyridines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Potent adjuvantic activity of a CCR1-agonistic bis-quinoline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Classification of scaffold-hopping approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Structure-activity relationships in toll-like receptor 2-agonists leading to simplified monoacyl lipopeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Endogenous toll-like receptor ligands and their biological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Structure-activity relationships in human toll-like receptor 7-active imidazoquinoline analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Molecular replacement with MOLREP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Regioisomerism-dependent TLR7 agonism and antagonism in an imidazoquinoline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Potential adjuvantic properties of innate immune stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Pathogen recognition by innate receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Comparison of the immunostimulatory and proinflammatory activities of candidate Gram-positive endotoxins, lipoteichoic acid, peptidoglycan, and lipopeptides, in murine and human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Toll-like receptor control of the adaptive immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Innate immune recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Selective transmission of R5-tropic HIV type 1 from dendritic cells to resting CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

6 July 2018

Structure-activity relationships in Toll-like receptor 7 agonistic 1H-imidazo[4,5-c]pyridines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

28 October 2018

The history of Toll-like receptors - redefining innate immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

28 October 2018

Structure-activity relationships in human Toll-like receptor 2-specific monoacyl lipopeptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

28 October 2018

Structure-activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic γ-glutamyldiaminopimelic acid derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

28 October 2018

Scaffold hopping in de novo design. Ligand generation in the absence of receptor information.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

28 October 2018

Density Functionals with Broad Applicability in Chemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191598

28 October 2018

Toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25192394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical investigations of Toll-like receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/25192394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multistep microwave-assisted divergent synthesis of indolo-fused pyrazino-/diazepinoquinoxalinones on PEG support

1 reference

https://pubmed.ncbi.nlm.nih.gov/25192394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scaffold hopping

1 reference

https://pubmed.ncbi.nlm.nih.gov/25192394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/25192394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM500744F

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25192394%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

release_wxo2hemq4zcnjj74ukfkwqsrga

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https://api.fatcat.wiki/v0/release/wxo2hemq4zcnjj74ukfkwqsrga

24 November 2022

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mapped directly with Wikidata item

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25192394%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

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Europe PubMed Central

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1 June 2020

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