(Q27681499)

1

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Hiromi Tanji

3

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Umeharu Ohto

4

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Subbalakshmi S Malladi

5

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Lauren M Fox

6

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Toshiyoki Shimizu

7

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Sunil A David

Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

8

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language of work or name

1 reference

April 2014

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published in

ChemMedChem

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volume

9

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issue

4

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page(s)

719-23

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Vaccines: the Fourth Century

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Pathogen recognition and innate immunity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Pattern recognition theory and the launch of modern innate immunity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

The interpretation of protein structures: Total volume, group volume distributions and packing density

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Approaching the asymptote? Evolution and revolution in immunology

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Toll-like receptor control of the adaptive immune responses

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Design and development of stable, water-soluble, human Toll-like receptor 2 specific monoacyl lipopeptides as candidate vaccine adjuvants.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

The ultra-potent and selective TLR8 agonist VTX-294 activates human newborn and adult leukocytes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo[4,5-c]quinolines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Potent adjuvanticity of a pure TLR7-agonistic imidazoquinoline dendrimer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Structure-activity relationships in human Toll-like receptor 8-active 2,3-diamino-furo[2,3-c]pyridines.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Potent adjuvantic activity of a CCR1-agonistic bis-quinoline

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

New insights into the regulation of signalling by toll-like receptors and nod-like receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Regulation of adaptive immunity by the innate immune system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Pathogen recognition by innate immunity and its signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

The roles of TLRs, RLRs and NLRs in pathogen recognition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Innate immunity of the newborn: basic mechanisms and clinical correlates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Synthesis and structure-activity-relationships of 1H-imidazo[4,5-c]quinolines that induce interferon production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Toll-like receptors and acquired immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Application and limitations of X-ray crystallographic data in structure-based ligand and drug design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Vaccines, Vaccination, and Vaccinology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Packing at the protein-water interface

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Exquisite selectivity for human toll-like receptor 8 in substituted furo[2,3-c]quinolines.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Structure-activity relationships in human toll-like receptor 7-active imidazoquinoline analogues

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Immunology: Toll-like receptors and antibody responses

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4105021

Innate and adaptive immunity: the 2011 Nobel Prize in Physiology or Medicine

2 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

The history of Toll-like receptors - redefining innate immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Toll-dependent control mechanisms of CD4 T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

CL097, a TLR7/8 ligand, inhibits TLR-4--dependent activation of IRAK-M and BCL-3 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Interferon-α suppressed granulocyte colony stimulating factor production is reversed by CL097, a TLR7/8 agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Structure-activity relationships in Toll-like receptor 7 agonistic 1H-imidazo[4,5-c]pyridines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Immunoprofiling toll-like receptor ligands: Comparison of immunostimulatory and proinflammatory profiles in ex vivo human blood models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Structure-activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic γ-glutamyldiaminopimelic acid derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Anwendung und Grenzen kristallographischer Daten im strukturbezogenen Liganden- und Wirkstoff-Design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Control of B-cell responses by Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300573

Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075

21 January 2018

1 reference

PubMed

12 December 2020

The TLR7/8 agonist CL097 primes N-formyl-methionyl-leucyl-phenylalanine-stimulated NADPH oxidase activation in human neutrophils: critical role of p47phox phosphorylation and the proline isomerase Pin1

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1002/CMDC.201300573

1 reference

release_wra6mjaoijbx7jbzrxm4ab7zeq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wra6mjaoijbx7jbzrxm4ab7zeq

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

PubMed publication ID

24474703

1 reference