(Q36069620)

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Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

toll-like receptor

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1 reference

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inferred from title

author name string

Victoria J Philbin

1

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Europe PubMed Central

PMC publication ID

12 August 2017

David J Dowling

2

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12 August 2017

Leighanne C Gallington

3

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12 August 2017

Guadalupe Cortés

4

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12 August 2017

Zhen Tan

5

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12 August 2017

Eugénie E Suter

6

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Europe PubMed Central

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12 August 2017

Kevin W Chi

7

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Europe PubMed Central

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12 August 2017

Ariel Shuckett

8

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12 August 2017

Liat Stoler-Barak

9

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Europe PubMed Central

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12 August 2017

Mark Tomai

10

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12 August 2017

Richard L Miller

11

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12 August 2017

Keith Mansfield

12

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12 August 2017

Ofer Levy

13

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12 August 2017

language of work or name

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publication date

21 April 2012

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12 August 2017

The Journal of Allergy and Clinical Immunology

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12 August 2017

130

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Europe PubMed Central

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12 August 2017

1

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Europe PubMed Central

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12 August 2017

195-204.e9

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Europe PubMed Central

PMC publication ID

12 August 2017

Development of newborn and infant vaccines

1 reference

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Age-dependent maturation of Toll-like receptor-mediated cytokine responses in Gambian infants

1 reference

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Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity

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Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities.

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Vaccine adjuvants: putting innate immunity to work

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TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity

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Acquisition of adult-like TLR4 and TLR9 responses during the first year of life

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Intracellular toll-like receptors

1 reference

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1 reference

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Neonatal innate TLR-mediated responses are distinct from those of adults.

1 reference

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Activating immunity: lessons from the TLRs and NLRs

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Neonatal innate immunity in allergy development

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Bacillus anthracis capsule activates caspase-1 and induces interleukin-1beta release from differentiated THP-1 and human monocyte-derived dendritic cells

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TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells

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Towards an understanding of the adjuvant action of aluminium

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Neonatal pneumococcal conjugate vaccine immunization primes T cells for preferential Th2 cytokine expression: a randomized controlled trial in Papua New Guinea

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Phenotype and function of neonatal DC.

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Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

1 reference

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Safety and efficacy of neonatal vaccination

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Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis

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Four million newborn deaths: is the global research agenda evidence-based?

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Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant

1 reference

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

1 reference

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Type I interferons as vaccine adjuvants against infectious diseases and cancer

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The antiviral activity of Toll-like receptor 7 and 7/8 agonists

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Immunostimulatory activity of Toll-like receptor 8 agonists towards human leucocytes: basic mechanisms and translational opportunities

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Adenosine deamination sustains dendritic cell activation in inflammation

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Innate immunity of the newborn: basic mechanisms and clinical correlates

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Shaping of monocyte and macrophage function by adenosine receptors

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The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn.

1 reference

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Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells

1 reference

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Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

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Combined Toll-like receptor agonists synergistically increase production of inflammatory cytokines in human neonatal dendritic cells.

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Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR-7 and -8 agonists as vaccine adjuvants

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal dendritic cells are intrinsically biased against Th-1 immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficient interferon-gamma receptor-mediated signaling in neonatal macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD1c(+) immature myeloid dendritic cells are predominant in cord blood of healthy neonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521247

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based on heuristic

inferred from PubMed ID database lookup

Pollen metabolome analysis reveals adenosine as a major regulator of dendritic cell–primed TH cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JACI.2012.02.042

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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