(Q34316177)

1 August 2017

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title

Regulation of mouse mammary gland development and tumorigenesis by the ERBB signaling network (English)

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1 August 2017

Troyer KL

1

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1 August 2017

Lee DC

series ordinal

2

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1 August 2017

publication date

1 January 2001

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Journal of Mammary Gland Biology and Neoplasia

1 August 2017

published in

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1 August 2017

volume

6

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1 August 2017

issue

1

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1 August 2017

page(s)

7-21

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https://scigraph.springernature.com/pub.10.1023/a:1009560330359

1 August 2017

exact match

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cites work

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Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice

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Exposure to diethylstilbestrol during a critical developmental period of the mouse reproductive tract leads to persistent induction of two estrogen-regulated genes.

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Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4

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Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation

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12 December 2020

Specificity within the EGF family/ErbB receptor family signaling network

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12 December 2020

The extracellular region of heregulin is sufficient to promote mammary gland proliferation and tumorigenesis but not apoptosis

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells

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12 December 2020

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12 December 2020

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12 December 2020

Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells

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Repression of cyclin D1: a novel function of MYC

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12 December 2020

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12 December 2020

Receptors for epidermal growth factor in the rat uterus

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12 December 2020

A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

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12 December 2020

Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli

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12 December 2020

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12 December 2020

A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line

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12 December 2020

Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells

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12 December 2020

Cell cycle basis for the onset and progression of c-Myc-induced, TGFalpha-enhanced mouse mammary gland carcinogenesis

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12 December 2020

Active signaling by Neu in transgenic mice

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12 December 2020

neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group

1 reference

12 December 2020

Ligands for ErbB-family receptors encoded by a neuregulin-like gene

1 reference

12 December 2020

Biosynthetic processing of neu differentiation factor. Glycosylation trafficking, and regulated cleavage from the cell surface

1 reference

12 December 2020

Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors

1 reference

12 December 2020

NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice

1 reference

12 December 2020

Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer

1 reference

12 December 2020

The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase

1 reference

12 December 2020

Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations.

1 reference

12 December 2020

Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development

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12 December 2020

Mammary gland development is mediated by both stromal and epithelial progesterone receptors

1 reference

12 December 2020

Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor

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12 December 2020

Receptor tyrosine kinases: specific outcomes from general signals

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12 December 2020

The oncogene heregulin induces apoptosis in breast epithelial cells and tumors

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12 December 2020

Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-beta

1 reference

12 December 2020

Blocking HER-2/HER-3 function with a dominant negative form of HER-3 in cells stimulated by heregulin and in breast cancer cells with HER-2 gene amplification.

1 reference

12 December 2020

c-erbB-3 protein expression in human breast cancer: comparison with other tumour variables and survival

1 reference

12 December 2020

Dynamic expression and activation of ERBB receptors in the developing mouse mammary gland

1 reference

12 December 2020

Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice

1 reference

12 December 2020

Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas

1 reference

12 December 2020

Regulation of epidermal growth factor receptor by estrogen

1 reference

12 December 2020

Local effects of EGF, alpha-TGF, and EGF-like growth factors on lobuloalveolar development of the mouse mammary gland in vivo

1 reference

12 December 2020

Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1009560330359

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Dimensions Publication ID

1 August 2017

1041468160

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