(Q34317385)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

author

Maria Carmela Vegliante

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Jean-Noël Freund

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

author name string

Salvatore Modica

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Marica Cariello

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Annalisa Morgano

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Isabelle Gross

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Stefania Murzilli

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Lorena Salvatore

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Carlo Sabbà

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Antonio Moschetta

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

language of work or name

English

0 references

publication date

19 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

13 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

28421-28432

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions

13 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and β-catenin activity in colon cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Cdx2 determines the fate of postnatal intestinal endoderm

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Bile acids and colon cancer: Solving the puzzle with nuclear receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Nuclear bile acid receptor FXR protects against intestinal tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

A real-time PCR method to rapidly titer adenovirus stocks.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Wnt/beta-catenin signaling in development and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Cdx1 and cdx2 expression during intestinal development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Bile acids: natural ligands for an orphan nuclear receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Identification of a nuclear receptor for bile acids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Mitogen-activated protein kinase activation regulates intestinal epithelial differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Homeosis and intestinal tumours in Cdx2 mutant mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

An intestine-specific homeobox gene regulates proliferation and differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

A genetic model for colorectal tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192494

CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.571513

Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.571513

Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.571513

Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.571513

The intestinal nuclear receptor signature with epithelial localization patterns and expression modulation in tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.571513

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.571513

Frequent rearrangements and amplification of the CDX2 homeobox gene in human sporadic colorectal cancers with chromosomal instability

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25138215

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiplex PCR analysis and genotype-phenotype correlations of frequent APC mutations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25138215

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.571513

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

25138215

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25138215%20AND%20SRC:MED&resulttype=core&format=json