(Q47629898)

4 February 2018

title

CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene (English)

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4 February 2018

author name string

Yun-Qing Bai

1

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4 February 2018

Satoshi Miyake

2

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4 February 2018

Takehisa Iwai

3

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4 February 2018

Yasuhito Yuasa

4

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4 February 2018

language of work or name

English

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publication date

1 September 2003

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4 February 2018

published in

Oncogene

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4 February 2018

volume

22

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4 February 2018

issue

39

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4 February 2018

page(s)

7942-7949

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4 February 2018

The p21(WAF1/CIP1) promoter is methylated in Rat-1 cells: stable restoration of p53-dependent p21(WAF1/CIP1) expression after transfection of a genomic clone containing the p21(WAF1/CIP1) gene

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Distinct expression of CDX2 and GATA4/5, development-related genes, in human gastric cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Homeosis and intestinal tumours in Cdx2 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

The Cdx-1 and Cdx-2 homeobox genes in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Analysis of wild-type and mutant p21WAF-1 gene activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

A molecular gradient in early Drosophila embryos and its role in specifying the body pattern.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Homeobox genes and axial patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

The homeobox gene Cdx1 belongs to the p53-p21(WAF)-Bcl-2 network in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Cdx1 and cdx2 expression during intestinal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Cdx1 promotes differentiation in a rat intestinal epithelial cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

A homeodomain protein related to caudal regulates intestine-specific gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

An intestine-specific homeobox gene regulates proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

7 January 2021

Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

7 January 2021

Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

7 January 2021

Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

7 January 2021

Conversion of gastric mucosa to intestinal metaplasia in Cdx2-expressing transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

7 January 2021

The murine Cdx1 gene product localises to the proliferative compartment in the developing and regenerating intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206634

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206634

1 reference

4 February 2018

1 reference

4 February 2018