(Q34318436)

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Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22737240%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22737240%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Santosh K. Misra

3

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6 February 2020

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6 February 2020

Santanu Bhattacharya

6

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6 February 2020

Kalappa Muniyappa

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K Muniyappa

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6 February 2020

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Ananya Paul

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6 February 2020

Akash K Jain

2

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6 February 2020

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21 June 2012

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6 February 2020

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Europe PubMed Central

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6 February 2020

7

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6 February 2020

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6 February 2020

e39467

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6 February 2020

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Creative Commons Attribution 4.0 International

21 June 2012

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April 2022 Public Data File from Crossref

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0 references

Dimeric 1,3-phenylene-bis(piperazinyl benzimidazole)s: synthesis and structure-activity investigations on their binding with human telomeric G-quadruplex DNA and telomerase inhibition properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Recent developments in the chemistry and biology of G-quadruplexes with reference to the DNA groove binders

1 reference

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Graphene as a nanocarrier for tamoxifen induces apoptosis in transformed cancer cell lines of different origins

1 reference

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6 July 2018

Interaction of G-quadruplexes with nonintercalating duplex-DNA minor groove binding ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Improvement of porphyrins for G-quadruplex DNA targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Induction of G-quadruplex DNA structure by Zn(II) 5,10,15,20-tetrakis(N-methyl-4-pyridyl)porphyrin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

G4 motifs correlate with promoter-proximal transcriptional pausing in human genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Structural insights into G-quadruplexes: towards new anticancer drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Groove binding ligands for the interaction with parallel-stranded ps-duplex DNA and triplex DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Telomeres and telomerase: from discovery to clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Duplex formation at the 5' end affects the quadruplex conformation of the human telomeric repeat overhang in sodium but not in potassium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

UV Melting of G-Quadruplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

BRACO19 analog dimers with improved inhibition of telomerase and hPot 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Medical implications of benzimidazole derivatives as drugs designed for targeting DNA and DNA associated processes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

TRAP-LIG, a modified telomere repeat amplification protocol assay to quantitate telomerase inhibition by small molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Molecular dynamics and principal components analysis of human telomeric quadruplex multimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Polymorphism of human telomeric quadruplex structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

G-quadruplex formation in human telomeric (TTAGGG)4 sequence with complementary strand in close vicinity under molecularly crowded condition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Fluorescence-based melting assays for studying quadruplex ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Investigation of spectral conversion of d(TTAGGG)4 and d(TTAGGG)13 upon potassium titration by a G-quadruplex recognizer BMVC molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Extension of G-quadruplex DNA by ciliate telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

The Amber biomolecular simulation programs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.

1 reference

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Development and testing of a general amber force field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Influence of phenyl ring disubstitution on bisbenzimidazole and terbenzimidazole cytotoxicity: synthesis and biological evaluation as radioprotectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Crystal structure of parallel quadruplexes from human telomeric DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

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Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

G-Quadruplex DNA as a target for drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Life at the End of the Chromosome: Telomeres and Telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

VMD: visual molecular dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

Structure and function of telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380826

6 July 2018

The tail of the telomere

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Structure of long human telomeric RNA (TERRA): G-quadruplexes formed by four and eight UUAGGG repeats are stable building blocks.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Synthesis and evaluation of a novel class of G-quadruplex-stabilizing small molecules based on the 1,3-phenylene-bis(piperazinyl benzimidazole) system

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Bis(benzimidazole)pyridine derivative as a new class of G-quadruplex inducing and stabilizing ligand

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Duplex dissociation of telomere DNAs induced by molecular crowding.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Drastic effect of a single base difference between human and tetrahymena telomere sequences on their structures under molecular crowding conditions.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Selective binding and inverse fluorescent behavior of magnesium ion by podand possessing plural imidazo[4,5-f]-1,10-phenanthroline groups and its Ru(II) complex

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

Comparison of simple potential functions for simulating liquid water

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039467

21 January 2018

High fluorescence selectivity and visual detection of G-quadruplex structures by a novel dinuclear ruthenium complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human telomeric DNA forms parallel-stranded intramolecular G-quadruplex in K+ solution under molecular crowding condition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Metal-Mediated Conformational Switch Controls G-Quadruplex Binding Affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic roles for G4 DNA in the biology of eukaryotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tridentate N-Donor Palladium(II) Complexes as Efficient Coordinating Quadruplex DNA Binders

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer: greater selectivity than monomer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence specificity of inter- and intramolecular G-quadruplex formation by human telomeric DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biophysical characterization of the human telomeric (TTAGGG)4 repeat in a potassium solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, DNA binding, and Leishmania topoisomerase inhibition activities of a novel series of anthra[1,2-d]imidazole-6,11-dione derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-quadruplex DNA: a target for drug design

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding properties of human telomeric quadruplex multimers: A new route for drug design

1 reference

https://pubmed.ncbi.nlm.nih.gov/22737240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0039467

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22737240%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2012PLoSO...739467P

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22737240%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22737240%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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