(Q34324276)

1 August 2017

title

Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension (English)

1 reference

1 August 2017

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Romain Perrier

8

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Sharad Kumar

object named as

Sharad Kumar

13

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author name string

Caroline Ronzaud

1

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1 August 2017

Dominique Loffing-Cueni

2

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1 August 2017

Pierrette Hausel

3

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1 August 2017

Anne Debonneville

4

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1 August 2017

Sumedha Ram Malsure

5

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1 August 2017

Nicole Fowler-Jaeger

6

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1 August 2017

Natasha A Boase

7

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1 August 2017

Marc Maillard

9

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1 August 2017

Baoli Yang

10

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1 August 2017

John B Stokes

11

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1 August 2017

Robert Koesters

12

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1 August 2017

Edith Hummler

14

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1 August 2017

Johannes Loffing

15

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1 August 2017

Olivier Staub

16

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1 August 2017

language of work or name

English

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publication date

25 January 2013

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Journal of Clinical Investigation

1 August 2017

published in

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1 August 2017

volume

123

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1 August 2017

issue

2

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1 August 2017

page(s)

657-665

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Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain

1 August 2017

cites work

1 reference

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Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype

6 July 2018

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Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

6 July 2018

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Is oxidative stress, a link between nephrolithiasis and obesity, hypertension, diabetes, chronic kidney disease, metabolic syndrome?

6 July 2018

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Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension

6 July 2018

1 reference

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Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway

6 July 2018

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Update on nephrolithiasis: beyond symptomatic urinary tract obstruction.

6 July 2018

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Respiratory distress and perinatal lethality in Nedd4-2-deficient mice

6 July 2018

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Sodium and potassium balance depends on αENaC expression in connecting tubule

6 July 2018

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Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension

6 July 2018

1 reference

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The evidence-based use of thiazide diuretics in hypertension and nephrolithiasis

6 July 2018

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Role of the WNK-activated SPAK kinase in regulating blood pressure

6 July 2018

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POSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels.

6 July 2018

1 reference

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Activation of the epithelial sodium channel (ENaC) by serine proteases

6 July 2018

1 reference

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An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

6 July 2018

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Deubiquitylation regulates activation and proteolytic cleavage of ENaC

6 July 2018

1 reference

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Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2

6 July 2018

1 reference

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Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

6 July 2018

1 reference

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The association of nephrolithiasis with hypertension and obesity: a review

6 July 2018

1 reference

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The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

6 July 2018

1 reference

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Role of ubiquitylation in cellular membrane transport

6 July 2018

1 reference

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Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.

6 July 2018

1 reference

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Relative contribution of Nedd4 and Nedd4-2 to ENaC regulation in epithelia determined by RNA interference

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

WNK kinases regulate thiazide-sensitive Na-Cl cotransport

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Human hypertension caused by mutations in WNK kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Mammalian distal tubule: physiology, pathophysiology, and molecular anatomy

6 July 2018

1 reference

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Aldosterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Hypokalemia in a mouse model of Gitelman's syndrome

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Dysfunction of the epithelial sodium channel expressed in the kidney of a mouse model for Liddle syndrome

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Pseudohypoaldosteronism type II: marked sensitivity to thiazides, hypercalciuria, normomagnesemia, and low bone mineral density

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Renal potassium transport: mechanisms and regulation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Aldosterone-induced increase in the abundance of Na+ channel subunits.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561795

Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics

28 October 2018

1 reference

12 December 2020

Dietary sodium intake regulates the ubiquitin-protein ligase nedd4-2 in the renal collecting system

1 reference

12 December 2020

Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule

1 reference

12 December 2020

Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model

1 reference

12 December 2020

Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates its ubiquitination

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI61110

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1 August 2017

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1 August 2017

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