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Ras and Rho regulation of the cell cycle and oncogenesis
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Ras and Rho regulation of the cell cycle and oncogenesis
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
author name string
Pruitt K
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
Der CJ
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
language of work or name
English
0 references
publication date
1 September 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
published in
Cancer Letters
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
volume
171
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
page(s)
1-10
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
cites work
Increasing complexity of Ras signaling.
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Understanding Ras: 'it ain't over 'til it's over'.
1 reference
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Crossref
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7 January 2021
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Ras and Rho GTPases: a family reunion
1 reference
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Crossref
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7 January 2021
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CDK inhibitors: positive and negative regulators of G1-phase progression
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7 January 2021
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The Rb/E2F pathway: expanding roles and emerging paradigms
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7 January 2021
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inferred from DOI database lookup
Cell cycle: routine role for Ras.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
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Cell cycle targets of Ras/Raf signalling
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
How do small GTPase signal transduction pathways regulate cell cycle entry?
1 reference
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Crossref
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Proteins regulating Ras and its relatives
1 reference
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Crossref
reference URL
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7 January 2021
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ras genes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras effectors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signalling and apoptosis
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras caught in another affair: the exchange factors for Ral.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
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inferred from DOI database lookup
Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
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inferred from DOI database lookup
Phospholipase C(epsilon): a novel Ras effector
1 reference
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reference URL
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7 January 2021
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Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells
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7 January 2021
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Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.
1 reference
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Crossref
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7 January 2021
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Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle-dependent activation of Ras.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple ras effector pathways contribute to G(1) cell cycle progression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rho family proteins and Ras transformation: the RHOad less traveled gets congested.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rho signals to cell growth and apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-dependent cell cycle commitment during G2 phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of potential effector molecules of the Ras-related GTPase Rap2
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of Rho signaling pathway promotes CNS axon regeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of exit from quiescence by p27 and cyclin D1-CDK4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperating oncogenes converge to regulate cyclin/cdk complexes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-containing cyclin kinases exist in both active and inactive states
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New functional activities for the p21 family of CDK inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational control of p27Kip1 accumulation during the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An analysis of Mek1 signaling in cell proliferation and transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases and signaling networks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases and their effector proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of c-myc expression by Ras/Raf signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900528-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0304-3835(01)00528-6
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
PubMed ID
11485822
1 reference
stated in
Europe PubMed Central
PubMed ID
11485822
retrieved
1 August 2017
ResearchGate publication ID
11857003
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