(Q34328580)

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PEG drugs: an overview

scientific article

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scholarly article

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Europe PubMed Central

1 August 2017

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Europe PubMed Central

PEG drugs: an overview (English)

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Europe PubMed Central

1 August 2017

author name string

Greenwald RB

1

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Europe PubMed Central

1 August 2017

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publication date

1 July 2001

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Europe PubMed Central

1 August 2017

Journal of Controlled Release

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Europe PubMed Central

1 August 2017

74

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Europe PubMed Central

1 August 2017

1-3

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Europe PubMed Central

1 August 2017

159-171

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Europe PubMed Central

1 August 2017

A branched monomethoxypoly(ethylene glycol) for protein modification

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On the suitability of urethane bonds between the carrier and the drug moiety in poly(ethyleneglycol)-based oligomeric prodrugs.

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Functionalized poly(ethylene glycol) for preparation of biologically relevant conjugates

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Drug delivery systems: water soluble taxol 2'-poly(ethylene glycol) ester prodrugs-design and in vivo effectiveness

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Distribution and tissue uptake of poly(ethylene glycol) with different molecular weights after intravenous administration to mice

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Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

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Prodrugs. Do they have advantages in clinical practice?

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Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier

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A novel connector linkage applicable in prodrug design

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Camptothecin-20-PEG ester transport forms: the effect of spacer groups on antitumor activity

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Synthesis of congeners and prodrugs. 3. Water-soluble prodrugs of taxol with potent antitumor activity

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Synthesis and evaluation of some water-soluble prodrugs and derivatives of taxol with antitumor activity

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Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo.

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Early phase tumor accumulation of macromolecules: a great difference in clearance rate between tumor and normal tissues.

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Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs

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Drug delivery systems. 2. Camptothecin 20-O-poly(ethylene glycol) ester transport forms

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20-O-acylcamptothecin derivatives: evidence for lactone stabilization.

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Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker

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The design of selectively-activated anti-cancer prodrugs for use in antibody-directed and gene-directed enzyme-prodrug therapies.

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Drug delivery systems employing 1,4- or 1,6-elimination: poly(ethylene glycol) prodrugs of amine-containing compounds

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Prodrug strategies based on intramolecular cyclization reactions

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Design of intramolecularly activated prodrugs

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Drug delivery systems based on trimethyl lock lactonization: poly(ethylene glycol) prodrugs of amino-containing compounds

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Detection and characterization of antibodies to PEG-IFN-alpha2b using surface plasmon resonance.

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Evaluation of a new reagent for covalent attachment of polyethylene glycol to proteins

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PEG thiazolidine-2-thione, a novel reagent for facile protein modification: conjugation of bovine hemoglobin

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Identifiers

10.1016/S0168-3659(01)00331-5

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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