(Q34328745)

1 August 2017

title

Metabolism of endocannabinoids and related N-acylethanolamines: canonical and alternative pathways (English)

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1 August 2017

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Natsuo Ueda

1

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1 August 2017

Kazuhito Tsuboi

series ordinal

2

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1 August 2017

Toru Uyama

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

21 February 2013

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1 August 2017

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1 August 2017

volume

280

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1 August 2017

issue

9

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1 August 2017

page(s)

1874-1894

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The endocannabinoid system as an emerging target of pharmacotherapy

1 August 2017

cites work

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Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

21 January 2018

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2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

21 January 2018

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N-acylethanolamines, anandamide and food intake.

21 January 2018

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The search for the palmitoylethanolamide receptor.

21 January 2018

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2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12152

Enzymological studies on the biosynthesis of N-acylethanolamines

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12152

Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol

21 January 2018

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The neurobiology and evolution of cannabinoid signalling

21 January 2018

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The N-acylethanolamine-mediated regulatory pathway in plants

21 January 2018

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N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans

21 January 2018

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N-Acylethanolamines and related compounds: aspects of metabolism and functions.

21 January 2018

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N-acylated glycerophospholipids and their derivatives

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12152

Pathways and mechanisms of N-acylethanolamine biosynthesis: can anandamide be generated selectively?

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12152

N-acylation of phosphatidylethanolamine and its biological functions in mammals

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12152

Occurrence, biosynthesis and functions of N-acylphosphatidylethanolamines (NAPE): not just precursors of N-acylethanolamines (NAE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Structure and function of fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The contribution of cyclooxygenase-2 to endocannabinoid metabolism and action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

N-Acylethanolamines and precursor phospholipids - relation to cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Discovery and characterization of a Ca2+-independent phosphatidylethanolamine N-acyltransferase generating the anandamide precursor and its congeners

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Cell signaling by endocannabinoids and their congeners: questions of selectivity and other challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Visualization by mass spectrometry of 2-dimensional changes in rat brain lipids, including N-acylphosphatidylethanolamines, during neonatal brain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Biosynthetic pathways of the endocannabinoid anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Molecular characterization of a phospholipase D generating anandamide and its congeners

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Marked activation of the N-acylphosphatidylethanolamine-hydrolyzing phosphodiesterase by divalent cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The stimulatory effect of phosphatidylethanolamine on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A biosynthetic pathway for anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Regional distribution and age-dependent expression of N-acylphosphatidylethanolamine-hydrolyzing phospholipase D in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A common haplotype in NAPEPLD is associated with severe obesity in a Norwegian population-based cohort (the HUNT study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Equilibrium in the hydrolysis and synthesis of cannabimimetic anandamide demonstrated by a purified enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

In vitro synthesis of arachidonoyl amino acids by cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Evidence for distinct roles in catalysis for residues of the serine-serine-lysine catalytic triad of fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Assignment of endogenous substrates to enzymes by global metabolite profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A missense mutation in human fatty acid amide hydrolase associated with problem drug use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Modulation of anxiety through blockade of anandamide hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Activation of the endocannabinoid system by organophosphorus nerve agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A second fatty acid amide hydrolase with variable distribution among placental mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A catalytically silent FAAH-1 variant drives anandamide transport in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Enzymological analysis of the tumor suppressor A-C1 reveals a novel group of phospholipid-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Molecular cloning and biological activity of a novel Ha-Ras suppressor gene predominantly expressed in skeletal muscle, heart, brain, and bone marrow by differential display using clonal mouse EC cells, ATDC5

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

cDNA cloning and characterization of human and mouse Ca(2+)-independent phosphatidylethanolamine N-acyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Generation of N-acylphosphatidylethanolamine by members of the phospholipase A/acyltransferase (PLA/AT) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Structure/Function Relationships of Adipose Phospholipase A2 Containing a Cys-His-His Catalytic Triad

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

HRASLS3 is a PPARgamma-selective target gene that promotes adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Regulation of peroxisomal lipid metabolism by catalytic activity of tumor suppressor H-rev107

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Solution structure of the N-terminal catalytic domain of human H-REV107--a novel circular permutated NlpC/P60 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Catabolism of N-acylethanolamine phospholipids by dog brain preparations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

GDE1/MIR16 is a glycerophosphoinositol phosphodiesterase regulated by stimulation of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Biosynthetic pathways of bioactive N-acylethanolamines in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Multiple pathways involved in the biosynthesis of anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

An acid amidase hydrolyzing anandamide as an endogenous ligand for cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional similarity to acid ceramidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The N-acylethanolamine-hydrolyzing acid amidase (NAAA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Molecular cloning and characterization of a human cDNA and gene encoding a novel acid ceramidase-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Proteolytic activation and glycosylation of N-acylethanolamine-hydrolyzing acid amidase, a lysosomal enzyme involved in the endocannabinoid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Mass spectrometric characterization of human N-acylethanolamine-hydrolyzing acid amidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Autoproteolytic cleavage and activation of human acid ceramidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Biochemical and mass spectrometric characterization of human N-acylethanolamine-hydrolyzing acid amidase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Predominant expression of lysosomal N-acylethanolamine-hydrolyzing acid amidase in macrophages revealed by immunochemical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Expression and secretion of N-acylethanolamine-hydrolysing acid amidase in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Endogenous molecules stimulating N-acylethanolamine-hydrolyzing acid amidase (NAAA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Esters, Retroesters, and a Retroamide of Palmitic Acid: Pool for the First Selective Inhibitors of N-Palmitoylethanolamine- Selective Acid Amidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Synthesis and structure-activity relationships of N-(2-oxo-3-oxetanyl)amides as N-acylethanolamine-hydrolyzing acid amidase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Design and synthesis of potent N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitor as anti-inflammatory compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Endocannabinoid-mediated control of synaptic transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Phospholipase C is a key enzyme regulating intracellular calcium and modulating the phosphoinositide balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Phosphatidic acid as the biosynthetic precursor of the endocannabinoid 2-arachidonoylglycerol in intact mouse neuroblastoma cells stimulated with ionomycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Evidence for the involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation in mouse ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Lysophosphoinositide-specific phospholipase C in rat brain synaptic plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

2-Arachidonoyl-sn-glycero-3-phosphate, an arachidonic acid-containing lysophosphatidic acid: occurrence and rapid enzymatic conversion to 2-arachidonoyl-sn-glycerol, a cannabinoid receptor ligand, in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Release of arachidonate from diglyceride in human platelets requires the sequential action of a diglyceride lipase and a monoglyceride lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Development of the first potent and specific inhibitors of endocannabinoid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Monoacylglycerol lipase - a target for drug development?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

A review on the monoacylglycerol lipase: at the interface between fat and endocannabinoid signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Structural basis for human monoglyceride lipase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Brain monoglyceride lipase participating in endocannabinoid inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Discovery and development of endocannabinoid-hydrolyzing enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Oxidative metabolism of endocannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

Evolutionary origins of the endocannabinoid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12152

21 January 2018

Identifiers

DOI

10.1111/FEBS.12152

1 reference

1 August 2017

1 reference