(Q34328828)

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Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period

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Europe PubMed Central

PubMed publication ID

1 August 2017

Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period (English)

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Europe PubMed Central

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1 August 2017

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Nahum Sonenberg

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Nahum Sonenberg

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1 August 2017

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Ajay M Shah

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Issei Komuro

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1 August 2017

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Takahito Tamai

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1 August 2017

Tomokazu Murakawa

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Tomokazu Murakawa

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1 August 2017

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Jota Oyabu

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1 August 2017

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Manabu Taneike

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Kyoji Horie

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1 August 2017

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Takafumi Oka

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1 August 2017

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Osamu Yamaguchi

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1 August 2017

Shungo Hikoso

3

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1 August 2017

Toshihiro Takeda

4

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1 August 2017

Hiroyuki Nakayama

9

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1 August 2017

Yoshihiro Uno

10

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1 August 2017

Kazuhiko Nishida

12

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1 August 2017

Junji Takeda

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1 August 2017

Kinya Otsu

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1 August 2017

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publication date

20 February 2013

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1 August 2017

Journal of Biological Chemistry

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1 August 2017

288

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1 August 2017

14

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1 August 2017

10176-10187

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1 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3617260/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Rheb is essential for murine development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Rheb1 is required for mTORC1 and myelination in postnatal brain development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

mTOR signaling at a glance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

AMPK phosphorylation of raptor mediates a metabolic checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Cardiac myocyte cell cycle control in development, disease, and regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Regulation of cap-dependent translation by eIF4E inhibitory proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

A highly efficient recombineering-based method for generating conditional knockout mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Regulation of translation initiation by FRAP/mTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Developmental regulation of myosin gene expression in mouse cardiac muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617260

6 July 2018

Rheb activates protein synthesis and growth in adult rat ventricular cardiomyocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.423640

21 January 2018

Pressure overload induces cardiac dysfunction and dilation in signal transducer and activator of transcription 6-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.423640

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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