(Q34330305)

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Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

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1 August 2017

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Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity (English)

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genome-wide association study

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Beate St Pourcain

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Terho Lehtimäki

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Mika Kähönen

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Marika Kaakinen

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Ferran Ballester

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Marjo-Riitta Järvelin

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Vincent W Jaddoe

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Hakon Hakonarson

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Johannes Kettunen

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Johannes Kettunen

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Susan Ring

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Diana L Cousminer

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Struan F.A. Grant

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Jonathan P Bradfield

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Carla M T Tiesler

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Carla M T Tiesler

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Early Growth Genetics (EGG) Consortium

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Early Growth Genetics (EGG) Consortium

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Shikta Das

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Claudia Flexeder

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Mònica Guxens

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Marcella Marinelli

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Olli P H Pietiläinen

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author name string

Diane J Berry

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Wei Ang

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H Rob Taal

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Ville Huikari

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Maria M Groen-Blokhuis

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Claus Holst

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Jaakko T Leinonen

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John R B Perry

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Jorma S Viikari

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ReproGen Consortium

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Elisabeth Widén

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Chris Power

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publication date

27 February 2013

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Human Molecular Genetics

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22

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13

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1 August 2017

2735-2747

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1 August 2017

A genome-wide association meta-analysis identifies new childhood obesity loci

1 reference

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Pubertal timing and growth influences cardiometabolic risk factors in adult males and females

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Growth in height in childhood and risk of coronary heart disease in adult men and women

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6 July 2018

An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design

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Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

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6 July 2018

Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

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Phenotype mining in CNV carriers from a population cohort

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Familial concordance for age at menarche: analyses from the Breakthrough Generations Study

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Metabonomic, transcriptomic, and genomic variation of a population cohort

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Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

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MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

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6 July 2018

Genetic inactivation of ERK1 and ERK2 in chondrocytes promotes bone growth and enlarges the spinal canal

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Hundreds of variants clustered in genomic loci and biological pathways affect human height

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Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits

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Distinct variants at LIN28B influence growth in height from birth to adulthood

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Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

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A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

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Age at puberty and the emerging obesity epidemic

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Genetic and environmental influences on pubertal timing assessed by height growth

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Germline mutations in HRAS proto-oncogene cause Costello syndrome

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GnRH activates ERK1/2 leading to the induction of c-fos and LHbeta protein expression in LbetaT2 cells

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6 July 2018

Age at menarche: secular trends and association with adult anthropometric measures

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Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

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6 July 2018

The genetic contribution to pubertal growth and development studied by longitudinal growth data on twins

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6 July 2018

Bmi in childhood and its association with height gain, timing of puberty, and final height

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Association between age at menarche and risk of diabetes in adults: results from the EPIC-Norfolk cohort study

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Childhood growth and age at menarche.

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27 October 2018

Continuing Positive Secular Growth Change in the Netherlands 1955–1997

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Critical growth phases for adult shortness

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The adolescent growth spurt of boys and girls of the Harpenden Growth Study

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Identifiers

10.1093/HMG/DDT104

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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