(Q34332764)

1 August 2017

Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering (English)

1 reference

1 August 2017

Wells JA

1

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1 August 2017

Cunningham BC

series ordinal

2

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1 August 2017

Graycar TP

series ordinal

3

1 reference

1 August 2017

Estell DA

series ordinal

4

1 reference

1 August 2017

language of work or name

English

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publication date

1 August 1987

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

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1 August 2017

84

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1 August 2017

5167-5171

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1 August 2017

15

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Crystal and molecular structure of chymotrypsin inhibitor 2 from barley seeds in complex with subtilisin Novo

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

The mechanism of the reaction of chymotrypsin with p-nitrophenyl acetate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Substituting an alpha-helix switches the sequence-specific DNA interactions of a repressor.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Crystal structure at 2.6 A resolution of the complex of subtilisin BPN' with streptomyces subtilisin inhibitor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Three-dimensional structure of fungal proteinase K reveals similarity to bacterial subtilisin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Cloning, sequencing, and secretion of Bacillusamyloliquefacienssubtillisin inBacillus subtilis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

On the size of the active site in proteases. I. Papain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Supercoil sequencing: a fast and simple method for sequencing plasmid DNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Engineering an enzyme by site-directed mutagenesis to be resistant to chemical oxidation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Cassette mutagenesis: an efficient method for generation of multiple mutations at defined sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Hydrogen bonding and biological specificity analysed by protein engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Replacing the complementarity-determining regions in a human antibody with those from a mouse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Designing substrate specificity by protein engineering of electrostatic interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Refined 1.2 A crystal structure of the complex formed between subtilisin Carlsberg and the inhibitor eglin c. Molecular structure of eglin and its detailed interaction with subtilisin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

In vivo formation and stability of engineered disulfide bonds in subtilisin.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Natural variation of tyrosyl-tRNA synthetase and comparison with engineered mutants.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Cloning, sequencing and expression of subtilisin Carlsberg from Bacillus licheniformis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

X-ray crystallographic study of boronic acid adducts with subtilisin BPN' (Novo). A model for the catalytic transition state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

DNA sequencing with chain-terminating inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Probing steric and hydrophobic effects on enzyme-substrate interactions by protein engineering.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

High-level expression in Escherichia coli of biologically active bovine growth hormone.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298815

Changing the binding specificity of a repressor by redesigning an alpha-helix

27 October 2018

1 reference

12 December 2020

The crystallographically determined structures of atypical strained disulfides engineered into subtilisin

1 reference

12 December 2020

Bacillus subtilis Requires a "Stringent" Shine-Dalgarno Region for Gene Expression

1 reference

12 December 2020

Redesigning trypsin: alteration of substrate specificity

1 reference

12 December 2020

Protein engineering of alcohol dehydrogenase--1. Effects of two amino acid changes in the active site of yeast ADH-1

1 reference

12 December 2020

Subtilisin. Stereochemical mechanism involving transition-state stabilization

1 reference

12 December 2020

Crystal and molecular structure of the inhibitor eglin from leeches in complex with subtilisin Carlsberg

1 reference

12 December 2020

Polypeptide halomethyl ketones bind to serine proteases as analogs of the tetrahedral intermediate. X-ray crystallographic comparison of lysine- and phenylalanine-polypeptide chloromethyl ketone-inhibited subtilisin

1 reference

12 December 2020

An x-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN'

1 reference

12 December 2020

Active human-yeast chimeric phosphoglycerate kinases engineered by domain interchange

1 reference

12 December 2020

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.84.15.5167

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1 August 2017

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1 August 2017

1 reference