(Q34333638)

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Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C. (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1 reference

based on heuristic

inferred from title

author name string

Anton B Guliaev

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Bo Hang

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

B Singer

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

language of work or name

0 references

publication date

20 May 2004

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Europe PubMed Central

PubMed publication ID

1 August 2017

number of pages

9

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based on heuristic

inferred from page(s)

Nucleic Acids Research

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

32

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2844-2852

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

describes a project that uses

molecular dynamics simulation

1 reference

based on heuristic

inferred from title

Raster3D: photorealistic molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Characterisation of new substrate specificities of Escherichia coli and Saccharomyces cerevisiae AP endonucleases

1 reference

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6 July 2018

Structural insights by molecular dynamics simulations into differential repair efficiency for ethano-A versus etheno-A adducts by the human alkylpurine-DNA N-glycosylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Novel activity of Escherichia coli mismatch uracil-DNA glycosylase (Mug) excising 8-(hydroxymethyl)-3,N4-ethenocytosine, a potential product resulting from glycidaldehyde reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Molecular dynamics simulation of nucleic acids: successes, limitations, and promise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

1 reference

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6 July 2018

Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism

1 reference

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6 July 2018

Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

1 reference

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6 July 2018

Going APE over ref-1.

1 reference

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6 July 2018

Sequence-dependent conformational perturbation in DNA duplexes containing an epsilonA.T mismatch using molecular dynamics simulation

1 reference

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6 July 2018

New insights into the structure of abasic DNA from molecular dynamics simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Nucleic acids: theory and computer simulation, Y2K.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Solution structure of an 11-mer duplex containing the 3, N(4)-ethenocytosine adduct opposite 2'-deoxycytidine: implications for the recognition of exocyclic lesions by DNA glycosylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1,N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease III and endonuclease IV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

A single cyclic p-benzoquinone adduct can destabilize a DNA oligonucleotide duplex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Evidence for a common active site for cleavage of an AP site and the benzene-derived exocyclic adduct, 3,N4-benzetheno-dC, in the major human AP endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

3'-phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Environmental exposure to benzene: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5' cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Role of the HAP1 protein in repair of oxidative DNA damage and regulation of transcription factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

VMD: visual molecular dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Instability and decay of the primary structure of DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Molecular modeling: an experimental tool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Rings of controversy around benzene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Repair of oxidative damage to DNA: enzymology and biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity

1 reference

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6 July 2018

Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Incision Activity of Human Apurinic Endonuclease (Ape) at Abasic Site Analogs in DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Rate of depurination of native deoxyribonucleic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Mutagenesis by apurinic/apyrimidinic sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Occurrence and relevance of chemically induced benign neoplasms in long-term carcinogenicity studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Detection of (3'-hydroxy)-3,N4-benzetheno-2'-deoxycytidine-3'-phosphate by 32P-postlabeling of DNA reacted with p-benzoquinone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Detection of 3'-hydroxy-1,N6-benzetheno-2'-deoxyadenosine 3'-phosphate by phosphorus-32 postlabeling of DNA reacted with p-benzoquinone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

6 July 2018

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419600

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cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III

1 reference

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Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme

1 reference

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Human HeLa cell enzymes that remove phosphoglycolate 3'-end groups from DNA

1 reference

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Benzene toxicity: a critical evaluation: hematotoxicity in humans

1 reference

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6 July 2018

Ion solvation thermodynamics from simulation with a polarizable force field

1 reference

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27 October 2018

Mutagenicity of benzoquinones for Ames Salmonella tester strains

1 reference

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27 October 2018

Synthesis and characterization of deoxyguanosine-benzoquinone adducts.

1 reference

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Variations in the behavioral responses to apomorphine in different strains of rats

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of the molecular dynamics structure of DNA in solution based on calculated and observed NMR NOESY volumes and dihedral angles from scalar coupling constants

1 reference

https://pubmed.ncbi.nlm.nih.gov/15155853

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/15155853

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of an apurinic/apyrimidinic endonuclease from HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15155853

12 December 2020

based on heuristic

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Deoxyguanosine adducts formed from benzoquinone and hydroquinone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15155853

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKH594

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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