(Q34342353)

1 August 2017

title

Furin overexpression suppresses tumor growth and predicts a better postoperative disease-free survival in hepatocellular carcinoma (English)

1 reference

1 August 2017

1 reference

hepatocellular carcinoma

1 reference

Ya-Hui Huang

1

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1 August 2017

Kwang-Huei Lin

2

1 reference

1 August 2017

Chen-Hsin Liao

3

1 reference

1 August 2017

Ming-Wei Lai

4

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1 August 2017

Yi-Hsin Tseng

5

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1 August 2017

Chau-Ting Yeh

6

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1 August 2017

language of work or name

English

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publication date

10 July 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

7

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1 August 2017

page(s)

e40738

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

10 July 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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Human testicular orphan receptor 4 enhances thyroid hormone receptor signaling

6 July 2018

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CD133-positive hepatocellular carcinoma in an area endemic for hepatitis B virus infection

6 July 2018

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The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model

6 July 2018

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Molecular targeted therapies in hepatocellular carcinoma

6 July 2018

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Thyroid hormone promotes cell invasion through activation of furin expression in human hepatoma cell lines

6 July 2018

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A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness

6 July 2018

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Inhibition of proprotein convertases: approaches to block squamous carcinoma development and progression.

6 July 2018

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Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.

6 July 2018

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Subcutaneous and intrahepatic growth of human hepatoblastoma in immunodeficient mice

6 July 2018

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Proprotein convertases: "master switches" in the regulation of tumor growth and progression

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Increased furin activity enhances the malignant phenotype of human head and neck cancer cells

6 July 2018

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Effect of bax, bcl-2 and bcl-xL on regulating apoptosis in tissues of normal liver and hepatocellular carcinoma

6 July 2018

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

6 July 2018

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Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy

6 July 2018

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Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells

6 July 2018

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Bcl-xL blocks transforming growth factor-beta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activation in prostate epithelial cells

6 July 2018

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The proprotein convertases furin and PACE4 play a significant role in tumor progression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Pro-protein convertase gene expression in human breast cancer

6 July 2018

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Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

TGFbeta1 regulates gene expression of its own converting enzyme furin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

The synthesis of inhibitors for processing proteinases and their action on the Kex2 proteinase of yeast

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Processing of transforming growth factor beta 1 precursor by human furin convertase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Elevated furin expression in aggressive human head and neck tumors and tumor cell lines

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040738

Transforming growth factor-beta 1-induced apoptosis is blocked by beta 1-integrin-mediated mitogen-activated protein kinase activation in human hepatoma cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040738

Increased expression of the pro-protein convertase furin predicts decreased survival in ovarian cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393699

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

27 October 2018

1 reference

12 December 2020

p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest

1 reference

12 December 2020

Furin directly cleaves proMMP-2 in the trans-Golgi network resulting in a nonfunctioning proteinase

1 reference

12 December 2020

MMTV-cre-mediated fur inactivation concomitant with PLAG1 proto-oncogene activation delays salivary gland tumorigenesis in mice

1 reference

12 December 2020

Hepatocellular carcinoma cell cycle: study of Long-Evans cinnamon rats.

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0040738

Identifiers

DOI

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1 August 2017

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1 August 2017

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