(Q42745858)

6 November 2017

title

Upregulation of the insulin receptor and type I insulin-like growth factor receptor are early events in hepatocarcinogenesis (English)

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6 November 2017

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Eiman Aleem

1

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6 November 2017

Dirk Nehrbass

2

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6 November 2017

Fritz Klimek

3

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6 November 2017

Doris Mayer

4

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6 November 2017

Peter Bannasch

5

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6 November 2017

language of work or name

English

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publication date

16 March 2011

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6 November 2017

published in

Toxicologic Pathology

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6 November 2017

volume

39

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6 November 2017

issue

3

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6 November 2017

page(s)

524-543

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Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone

6 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The insulin receptor substrate-1: a biomarker for cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The WT1 Wilms' tumor suppressor gene: a novel target for insulin-like growth factor-I action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Overexpression of insulin receptor substrate-2 in human and murine hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Dysregulation of growth factor signaling in human hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The association between diabetes and hepatocellular carcinoma: a systematic review of epidemiologic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Potential significance of phenotypic heterogeneity of focal lesions at different stages in hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Insulin receptor, insulin receptor substrate-1, Raf-1, and Mek-1 during hormonal hepatocarcinogenesis by intrahepatic pancreatic islet transplantation in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Tumor lysis syndrome after transarterial chemoembolization of hepatocellular carcinoma: case reports and literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The mechanism of insulin-induced signal transduction mediated by the insulin receptor substrate family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The effects of insulin-like growth factors on tumorigenesis and neoplastic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Biochemical microanalysis of glycogen content and glucose-6-phosphate dehydrogenase activity in focal lesions of the rat liver induced by N-nitrosomorpholine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Overexpression of insulin receptor substrate-1, but not insulin receptor substrate-2, protects a T cell hybridoma from activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Molecular targeted therapies in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Serum insulin-like growth factor I evaluation as a useful tool for predicting the risk of developing hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis: a prospective study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The dose dependence and sequential appearance of putative preneoplastic populations induced in the rat liver by stop experiments with N-nitrosomorpholine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Insulin and insulin-like growth factor signalling in neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The role of the IGF system in cancer growth and metastasis: overview and recent insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Characterization of the insulin-like growth factor axis in a human hepatoma cell line (PLC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

The IGF axis and hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Insulin and insulin-like growth factor I regulate the same biological functions in HEP-G2 cells via their own specific receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Enzymology of cancer cells (first of two parts).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiments by oral exposure to N-nitrosomorpholine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

IRS proteins and the common path to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Novel inhibitors in development for hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Nuclear insulin receptor substrate-1 activates promoters of cell cycle progression genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Role of the insulin-like growth factor family in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Cell proliferation and cell death (apoptosis) in hepatic preneoplasia and neoplasia are closely related to phenotypic cellular diversity and instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310396905

21 January 2018

Identifiers

DOI

10.1177/0192623310396905

1 reference

6 November 2017

1 reference