(Q37292760)

19 August 2017

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title

The insulin receptor substrate-1: a biomarker for cancer? (English)

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19 August 2017

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1 reference

Renato Baserga

1

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PubMed ID

18851963

19 August 2017

language of work or name

English

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publication date

1 October 2008

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Experimental Cell Research

19 August 2017

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19 August 2017

315

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19 August 2017

5

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19 August 2017

727-732

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

19 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

The IGF‐1 receptor in cancer biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

The insulin-like growth factor-I receptor as a target for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Insulin-like growth factor I receptor signaling in transformation by src oncogenes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

The constitutively active mutant Galpha13 transforms mouse fibroblast cells deficient in insulin-like growth factor-I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Regulation of IGF-I receptor signaling in tumor cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

The contradictions of the insulin-like growth factor 1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Insulin receptor substrate-1 regulates the transformed phenotype of BT-20 human mammary cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and beta-catenin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

An essential role for protein synthesis in oncogenic cellular transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Insulin-like growth factor I receptor signaling and nuclear translocation of insulin receptor substrates 1 and 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Insulin receptor substrate 1 translocation to the nucleus by the human JC virus T-antigen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Nuclear translocation of insulin receptor substrate-1 by the simian virus 40 T antigen and the activated type 1 insulin-like growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Nuclear insulin receptor substrate-1 activates promoters of cell cycle progression genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

A modified tandem affinity purification tag technique for the purification of protein complexes in mammalian cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Association of insulin receptor substrate 1 with simian virus 40 large T antigen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

The role of insulin receptor substrate-1 in the oncogenicity of simian virus 40 T antigen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

The role of insulin receptor substrate-1 in transformation by v-src

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Constitutive and Growth Factor-Regulated Phosphorylation of Caveolin-1 Occurs at the Same Site (Tyr-14) in Vivo: Identification of a c-Src/Cav-1/Grb7 Signaling Cassette

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Regulation of insulin receptor substrate-1 expression levels by caveolin-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

The colorectal microRNAome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Principles of microRNA regulation of a human cellular signaling network

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Molecular markers of IGF-I-mediated mitogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

Insulin receptor substrate (IRS)-1 regulates murine embryonic stem (mES) cells self-renewal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.017

10.1016/J.YEXCR.2008.09.017

7 January 2021

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18851963