(Q36219706)

12 August 2017

1 reference

title

The insulin-like growth factor-I receptor as a target for cancer therapy (English)

1 reference

12 August 2017

1 reference

Renato Baserga

1

1 reference

PubMed ID

16083341

12 August 2017

language of work or name

English

0 references

publication date

1 August 2005

1 reference

Expert Opinion on Therapeutic Targets

12 August 2017

1 reference

12 August 2017

9

1 reference

12 August 2017

4

1 reference

12 August 2017

753-768

1 reference

Structure and function of the type 1 insulin-like growth factor receptor.

12 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Evidence for a differential interaction of SHC and the insulin receptor substrate-1 (IRS-1) with the insulin-like growth factor-I (IGF-I) receptor in the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

The contradictions of the insulin-like growth factor 1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Role of the IGF-I receptor in the regulation of cell-cell adhesion: implications in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Regulation of IGF-I receptor signaling in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Regulation of Mammalian Ribosomal Gene Transcription by RNA Polymerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Systematic identification of pathways that couple cell growth and division in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Drosophila S6 kinase: a regulator of cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Interleukin 3-dependent survival by the Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Coordinated decreases in rRNA gene transcription factors and rRNA synthesis during muscle cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Nuclear translocation of insulin receptor substrate-1 by the simian virus 40 T antigen and the activated type 1 insulin-like growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Insulin-like growth factor I receptor signaling and nuclear translocation of insulin receptor substrates 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Insulin receptor substrate-1 is present in hepatocyte nuclei from intact rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Nuclear translocation of insulin receptor substrate-1 by the insulin receptor in mouse embryo fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Regulation of upstream binding factor 1 activity by insulin-like growth factor I receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Insulin-like growth factors and neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

The effects of insulin-like growth factors on tumorigenesis and neoplastic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

The IGF‐1 receptor in cancer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Role of pescadillo in the transformation and immortalization of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Molecular markers of IGF-I-mediated mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

AGAR SUSPENSION CULTURE FOR THE SELECTIVE ASSAY OF CELLS TRANSFORMED BY POLYOMA VIRUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

The insulin like growth factor-1 receptor (IGF-1R) as a drug target: novel approaches to cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Inhibition of carcinoma cell growth and metastasis by a vesicular stomatitis virus G-pseudotyped retrovector expressing type I insulin-like growth factor receptor antisense

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.753

21 January 2018

Identifiers

DOI

10.1517/14728222.9.4.753

1 reference

12 August 2017

1 reference

PubMed ID

16083341