(Q42508340)

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Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 November 2017

Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

author name string

Macaulay VM

1

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Salisbury AJ

2

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Bohula EA

3

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Playford MP

4

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Smorodinsky NI

5

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Shiloh Y

6

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

language of work or name

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publication date

1 July 2001

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

30

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

4029-4040

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204565

0 references

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

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21 January 2018

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

1 reference

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21 January 2018

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage

1 reference

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21 January 2018

Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase inhibitors, Wortmannin or LY294002, inhibited accumulation of p21 protein after gamma-irradiation by stabilization of the protein

1 reference

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21 January 2018

Insulin-like growth factor (IGF)-I rescues breast cancer cells from chemotherapy-induced cell death--proliferative and anti-apoptotic effects

1 reference

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21 January 2018

Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Antisense ATM gene therapy: a strategy to increase the radiosensitivity of human tumors

1 reference

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21 January 2018

Overexpression and mutations of p53 in metastatic malignant melanomas

1 reference

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21 January 2018

A monoclonal antibody to the T‐cell receptor increases IGF‐I receptor content in normal T‐lymphocytes: Comparison with phytohemagglutinin

1 reference

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21 January 2018

Mutation and altered expression of p53 genes in experimental rat bladder tumor cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

The many substrates and functions of ATM

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

The effects of insulin-like growth factors on tumorigenesis and neoplastic growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

ATM associates with and phosphorylates p53: mapping the region of interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Cancer risk and the ATM gene: a continuing debate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Ionizing radiation activates the ATM kinase throughout the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Radiosensitive melanoma cell line with mutation of the gene for ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

ATM: a mediator of multiple responses to genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

ATM and ATR: networking cellular responses to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Up-regulation of macrophage wnt gene expression in adenoma-carcinoma progression of human colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Isolation of radiosensitive and radioresistant mutants from a medulloblastoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Dual roles of ATM in the cellular response to radiation and in cell growth control.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Diminished G1 checkpoint after gamma-irradiation and altered cell cycle regulation by insulin-like growth factor II overexpression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

21 January 2018

Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

The IGF-I receptor in cell growth, transformation and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

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Expression of insulin-like growth factor-1 receptor (IGF-1R) and p27Kip1 in melanocytic tumors: a potential regulatory role of IGF-1 pathway in distribution of p27Kip1 between different cyclins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

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Recovery from radiation damage in human squamous carcinoma of the cervix

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7 January 2021

based on heuristic

inferred from DOI database lookup

Silver-stained comet assay for detection of apoptosis

1 reference

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7 January 2021

based on heuristic

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Type I and II insulin-like growth factor receptors on human phytohemagglutinin-activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

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Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

Two new tubulins differ in a split decision

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

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Insulin-like growth factors and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 and ATM: cell cycle, cell death, and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of the insulin-like growth factor I receptor on ionizing radiation-induced cell death in mouse embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

Repopulation between radiation fractions in human melanoma xenografts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

ATM: sounding the double-strand break alarm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of oncogene expression using vector-generated RNA antisense

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of epidermal growth factor on the growth and radiation sensitivity of human breast cancer cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

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A p53 and apoptotic independent role for p21waf1 in tumour response to radiation therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204565

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1204565

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

ResearchGate publication ID

0 references

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