(Q35132648)

6 August 2017

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title

ATM: sounding the double-strand break alarm (English)

1 reference

6 August 2017

Shiloh Y

1

1 reference

6 August 2017

publication date

1 January 2000

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Cold Spring Harbor Symposia on Quantitative Biology

6 August 2017

published in

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6 August 2017

volume

65

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6 August 2017

page(s)

527-533

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Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Emerging roles of BRCA1 in transcriptional regulation and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Nijmegen breakage syndrome: consequences of defective DNA double strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM-dependent phosphorylation of nibrin in response to radiation exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Partners and pathwaysrepairing a double-strand break.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Global response of Saccharomyces cerevisiae to an alkylating agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

DNA double strand break repair in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Regulation of p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

The genetic defect in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Regulation and function of the p53-related proteins: same family, different rules

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Sensing and responding to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

NF-kappaB as a primary regulator of the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

MDM2--master regulator of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Regulation of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

The Mre11 complex and ATM: collaborating to navigate S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

The ATM protein is required for sustained activation of NF-kappaB following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM: a mediator of multiple responses to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Interaction between ATM protein and c-Abl in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

c-Abl: activation and nuclear targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Protective roles for ATM in cellular response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

The stress-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Localization of a portion of extranuclear ATM to peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Insights into the functions of BRCA1 and BRCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2000.65.527

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.7792600

Identifiers

DOI

10.1101/SQB.2000.65.527

1 reference

6 August 2017

1 reference