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c-Abl: activation and nuclear targets
scientific article (publication date: 2000)
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Europe PubMed Central
title
c-Abl: activation and nuclear targets
(English)
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author name string
Y Shaul
series ordinal
1
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language of work or name
English
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publication date
January 2000
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published in
Cell Death & Differentiation
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volume
7
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page(s)
10-6
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issue
1
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cites work
Cycling, stressed-out and nervous: cellular functions of c-Abl
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Modular binding domains in signal transduction proteins
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Identification of a ten-amino acid proline-rich SH3 binding site
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
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Interaction between ATM protein and c-Abl in response to DNA damage
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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inferred from DOI database lookup
The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFXI, a protein that binds the enhancers of several viruses and cell-cycle regulated genes
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
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SH2 domains recognize specific phosphopeptide sequences
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Leukoregulin induction of prostaglandin-endoperoxide H synthase-2 in human orbital fibroblasts. An in vitro model for connective tissue inflammation
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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inferred from DOI database lookup
Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
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SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Three-dimensional structure of the tyrosine kinase c-Src
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
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Crystal structure of the Src family tyrosine kinase Hck
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
An intramolecular SH3-domain interaction regulates c-Abl activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interaction between DNA-PK and c-Abl in response to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA binding domain of the human c-Abl tyrosine kinase preferentially binds to DNA sequences containing an AAC motif and to distorted DNA structures
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-abl has a sequence-specific enhancer binding activity
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
p140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Src homology 2 domain as a specificity determinant in the c-Abl-mediated tyrosine phosphorylation of the RNA polymerase II carboxyl-terminal repeated domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Rad51 function by c-Abl in response to DNA damage
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
A single HMG domain in high-mobility group 1 protein binds to DNAs as small as 20 base pairs containing the major cisplatin adduct
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and ATM: cell cycle, cell death, and cancer.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
The nuclear tyrosine kinase c-Abl negatively regulates cell growth
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Three distinct signalling responses by murine fibroblasts to genotoxic stress
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
Essential roles for the Abl and Arg tyrosine kinases in neurulation
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Abl neutralizes the inhibitory effect of Mdm2 on p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage and cell cycle regulation of ribonucleotide reductase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased sensitivity to apoptotic stimuli in c-abl-deficient progenitor B-cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-apoptotic effect of the c-Abl tyrosine kinase in the cellular response to 1-beta-D-arabinofuranosylcytosine
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 is a simian [correction of human] p53-related protein that can induce apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
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7 January 2021
based on heuristic
inferred from DOI database lookup
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400626
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4400626
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PubMed ID
10713716
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ResearchGate publication ID
12601556
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Springer Nature article ID
10.1038/sj.cdd.4400626
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