(Q40966247)

25 September 2017

title

c-Abl neutralizes the inhibitory effect of Mdm2 on p53. (English)

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25 September 2017

R V Sionov

1

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25 September 2017

E Moallem

2

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25 September 2017

M Berger

3

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25 September 2017

A Kazaz

4

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25 September 2017

O Gerlitz

5

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25 September 2017

Y Ben-Neriah

6

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25 September 2017

M Oren

7

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25 September 2017

Y Haupt

8

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25 September 2017

language of work or name

English

0 references

publication date

1 March 1999

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Journal of Biological Chemistry

25 September 2017

published in

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25 September 2017

volume

274

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25 September 2017

issue

13

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25 September 2017

page(s)

8371-8374

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p53, the cellular gatekeeper for growth and division

25 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Mdm-2: "big brother" of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Three distinct signalling responses by murine fibroblasts to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Functional interaction between DNA-PK and c-Abl in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8371

21 January 2018

Identifiers

DOI

10.1074/JBC.274.13.8371

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25 September 2017

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