(Q41075555)

26 September 2017

title

The constitutively active mutant Galpha13 transforms mouse fibroblast cells deficient in insulin-like growth factor-I receptor (English)

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26 September 2017

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4

LeRoith D

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26 September 2017

Liu JL

1

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26 September 2017

Blakesley VA

series ordinal

2

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26 September 2017

Gutkind JS

series ordinal

3

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26 September 2017

language of work or name

English

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publication date

1 November 1997

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Journal of Biological Chemistry

26 September 2017

number of pages

4

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based on heuristic

inferred from page(s)

published in

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26 September 2017

volume

272

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26 September 2017

issue

47

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26 September 2017

page(s)

29438-29441

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Molecular and cellular aspects of the insulin-like growth factor I receptor

26 September 2017

cites work

1 reference

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

21 January 2018

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The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

21 January 2018

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G proteins: transducers of receptor-generated signals

21 January 2018

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Ionic Channels and Their Regulation by G Protein Subunits

21 January 2018

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G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits

21 January 2018

1 reference

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Activation of Jun kinase/stress-activated protein kinase by GTPase-deficient mutants of G alpha 12 and G alpha 13.

21 January 2018

1 reference

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Galpha12 and Galpha13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29438

Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29438

G12 and G13 alpha-subunits are immunochemically detectable in most membranes of various mammalian cells and tissues.

21 January 2018

1 reference

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A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

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Potent transforming activity of the G13 alpha subunit defines a novel family of oncogenes

21 January 2018

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The transforming activity of activated G alpha 12.

21 January 2018

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Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

21 January 2018

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Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells

21 January 2018

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Tyrosine residues in the C-terminal domain of the insulin-like growth factor-I receptor mediate mitogenic and tumorigenic signals

21 January 2018

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Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-I receptor abolishes autophosphorylation but does not eliminate biologic function

21 January 2018

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The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families

21 January 2018

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Galpha12 and galpha13 are phosphorylated during platelet activation

21 January 2018

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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

21 January 2018

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Insulin-like growth factor I receptor signaling in transformation by src oncogenes

21 January 2018

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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

21 January 2018

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Insulin-like growth factors and cancer

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.47.29438

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26 September 2017

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