(Q34343100)

1 August 2017

title

Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes (English)

1 reference

1 August 2017

Thomas H Meek

1

1 reference

1 August 2017

Miles E Matsen

2

1 reference

1 August 2017

Vincent Damian

3

1 reference

1 August 2017

Alex Cubelo

4

1 reference

1 August 2017

Streamson C Chua

5

1 reference

1 August 2017

Gregory J Morton

6

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1 August 2017

language of work or name

English

0 references

publication date

19 August 2014

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1 August 2017

number of pages

11

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inferred from page(s)

published in

Endocrinology

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1 August 2017

volume

155

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1 August 2017

issue

11

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1 August 2017

page(s)

4157-4167

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Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin

1 August 2017

cites work

1 reference

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Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia

6 July 2018

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In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue

6 July 2018

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BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production

6 July 2018

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Metabolic manifestations of insulin deficiency do not occur without glucagon action

6 July 2018

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Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin

6 July 2018

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Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

6 July 2018

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Central nervous control of energy and glucose balance: focus on the central melanocortin system

6 July 2018

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6 July 2018

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Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice

6 July 2018

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Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia

6 July 2018

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Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity

6 July 2018

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Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

6 July 2018

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Leptin deficiency causes insulin resistance induced by uncontrolled diabetes

6 July 2018

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Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs

6 July 2018

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A functional melanocortin system may be required for chronic CNS-mediated antidiabetic and cardiovascular actions of leptin

6 July 2018

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6 July 2018

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Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome

6 July 2018

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Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

6 July 2018

1 reference

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Leptin and the regulation of the hypothalamic-pituitary-adrenal axis.

6 July 2018

1 reference

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Role of melanocortin signaling in the regulation of the hypothalamic-pituitary-thyroid (HPT) axis.

6 July 2018

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6 July 2018

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Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice

6 July 2018

1 reference

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Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Long-term orexigenic effects of AgRP-(83---132) involve mechanisms other than melanocortin receptor blockade

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Central nervous system control of food intake

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Involvement of agouti-related protein, an endogenous antagonist of hypothalamic melanocortin receptor, in leptin action

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Evidence that elevated plasma corticosterone levels are the cause of reduced hypothalamic corticotrophin-releasing hormone gene expression in diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Melanocortin receptors in leptin effects.

6 July 2018

1 reference

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Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice

6 July 2018

1 reference

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Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Role of leptin in the neuroendocrine response to fasting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Stimulatory effect of norepinephrine on ketogenesis in normal and insulin-deficient humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

The effect of experimental insulin deficiency on glucagon secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

The psychoneuroendocrinology of diabetes mellitus in rodents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Pancreatic extracts. 1922.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Hypothalamo-hypophysial-thyroid axis in streptozotocin-induced diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Endogenous BDNF regulates inhibitory synaptic transmission in the ventromedial nucleus of the hypothalamus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Central leptin acutely reverses diet-induced hepatic insulin resistance

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Melanocortin-independent effects of leptin on hepatic glucose fluxes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Role of melanocortin-4 receptors in mediating renal sympathoactivation to leptin and insulin.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Central leptin increases insulin sensitivity in streptozotocin-induced diabetic rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Modification of catecholamine-induced changes in heart function by food restriction in rats.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Intracerebroventricular administration of neuropeptide Y to normal rats has divergent effects on glucose utilization by adipose tissue and skeletal muscle.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197991

Studies of the development of diabetic ketosis in the rat

27 October 2018

1 reference

12 December 2020

Glucagon: Role in the Hyperglycemia of Diabetes Mellitus

1 reference

12 December 2020

Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon

1 reference

12 December 2020

Hyperglucagonemia and its suppression. Importance in the metabolic control of diabetes

1 reference

12 December 2020

Chronic antidiabetic and cardiovascular actions of leptin: role of CNS and increased adrenergic activity

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2014-1169

1 reference

1 August 2017

1 reference

1 August 2017

1 reference