(Q37110960)

18 August 2017

Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia (English)

1 reference

18 August 2017

1 reference

4

Stephan J Guyenet

1 reference

18 August 2017

Thomas H Meek

1

1 reference

18 August 2017

Miles E Matsen

2

1 reference

18 August 2017

Mauricio D Dorfman

3

1 reference

18 August 2017

Vincent Damian

5

1 reference

18 August 2017

Hong T Nguyen

6

1 reference

18 August 2017

Gerald J Taborsky

7

1 reference

18 August 2017

Gregory J Morton

8

1 reference

18 August 2017

language of work or name

English

0 references

publication date

19 June 2013

1 reference

18 August 2017

1 reference

18 August 2017

154

1 reference

18 August 2017

9

1 reference

18 August 2017

3067-3076

1 reference

In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin and the central nervous system control of glucose metabolism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Molecular mapping of mouse brain regions innervated by leptin receptor-expressing cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

SF-1 in the ventral medial hypothalamic nucleus: a key regulator of homeostasis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Innervation of skeletal muscle by leptin receptor-containing neurons

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin deficiency causes insulin resistance induced by uncontrolled diabetes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Distinct effects of leptin and a melanocortin receptor agonist injected into medial hypothalamic nuclei on glucose uptake in peripheral tissues

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

A functional melanocortin system may be required for chronic CNS-mediated antidiabetic and cardiovascular actions of leptin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Central leptin gene therapy, a substitute for insulin therapy to ameliorate hyperglycemia and hyperphagia, and promote survival in insulin-deficient diabetic mice.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

LRb signals act within a distributed network of leptin-responsive neurones to mediate leptin action

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Distributed neural control of energy balance: contributions from hindbrain and hypothalamus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin receptor long-form splice-variant protein expression in neuron cell bodies of the brain and co-localization with neuropeptide Y mRNA in the arcuate nucleus.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Role of central neural mechanisms in the regulation of hepatic glucose metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Region-specific leptin resistance within the hypothalamus of diet-induced obese mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Development of a steroidogenic factor 1/Cre transgenic mouse line

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Central leptin increases insulin sensitivity in streptozotocin-induced diabetic rats

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Role of the sympathetic nervous system and insulin in enhancing glucose uptake in peripheral tissues after intrahypothalamic injection of leptin in rats

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749482

Low plasma leptin levels contribute to diabetic hyperphagia in rats

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23782941

12 December 2020

inferred from PubMed ID database lookup

Chronic antidiabetic and cardiovascular actions of leptin: role of CNS and increased adrenergic activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23782941

12 December 2020

inferred from PubMed ID database lookup

Differential accessibility of circulating leptin to individual hypothalamic sites

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23782941

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1210/EN.2013-1328

1 reference

release_5lekepk5ozdd3gx2xadlrg5exy

18 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5lekepk5ozdd3gx2xadlrg5exy

24 November 2022

mapped directly with Wikidata item

1 reference

18 August 2017

PubMed publication ID

23782941

1 reference