(Q34343851)

English

Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER)

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23660123%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER) (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23660123%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

phase I clinical trial

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basal-cell carcinoma

1 reference

based on heuristic

inferred from title

Richard Scolyer

6

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1 March 2020

Levon Khachigian

18

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1 March 2020

Paula T. Hammond

11

object named as

Paula T Hammond

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1 March 2020

author name string

Eun-Ae Cho

1

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1 March 2020

Fergal J Moloney

2

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1 March 2020

Hong Cai

3

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1 March 2020

Annie Au-Yeung

4

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1 March 2020

Carlos China

5

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1 March 2020

Benafsha Yosufi

7

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1 March 2020

Mark J Raftery

8

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1 March 2020

Jason Z Deng

9

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1 March 2020

Stephen W Morton

10

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1 March 2020

Hendrik-Tobias Arkenau

12

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1 March 2020

Diona L Damian

13

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1 March 2020

Douglas J Francis

14

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1 March 2020

Colin N Chesterman

15

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1 March 2020

Ross St C Barnetson

16

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1 March 2020

Gary M Halliday

17

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1 March 2020

language of work or name

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publication date

7 May 2013

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1 March 2020

1 reference

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1 March 2020

381

1 reference

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1 March 2020

9880

1 reference

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1 March 2020

1835-1843

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23660123%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

DNAzyme targeting c-jun suppresses skin cancer growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

c-Jun promotes whereas JunB inhibits epidermal neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

c-Jun regulates shear- and injury-inducible Egr-1 expression, vein graft stenosis after autologous end-to-side transplantation in rabbits, and intimal hyperplasia in human saphenous veins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Cooperation between GLI and JUN enhances transcription of JUN and selected GLI target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

c-Jun Is critical for the progression of osteosarcoma: proof in an orthotopic spontaneously metastasizing model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Involvement of c-jun in human liposarcoma growth: supporting data from clinical immunohistochemistry and DNAzyme efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

DNAzyme technology and cancer therapy: cleave and let die.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Squamous cell carcinoma growth in mice and in culture is regulated by c-Jun and its control of matrix metalloproteinase-2 and -9 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Non-melanoma skin cancer in Australia: the 2002 national survey and trends since 1985.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Matrix metalloproteinase expression in basal cell carcinoma: relationship between enzyme profile and collagen fragmentation pattern

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Effect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

AP-1: a double-edged sword in tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Fortuitous convergences: the beginnings of JUN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Carcinogenesis of basal cell carcinomas: genetics and molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

AP-1 in mouse development and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Biology of basal cell carcinoma (Part II).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Biology of basal cell carcinoma (Part I).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

6 July 2018

Incidence estimate of nonmelanoma skin cancer in the United States, 2006.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

27 October 2018

c-Jun DNAzymes inhibit myocardial inflammation, ROS generation, infarct size, and improve cardiac function after ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

27 October 2018

The role of c-jun in PDTC-sensitive flow-dependent restenosis after angioplasty and stenting.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951714

27 October 2018

Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2962166-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of the AP-1 transcription factor family members in human colorectal epithelial and neuroendocrine neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2962166-7

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Jun regulates vascular smooth muscle cell growth and neointima formation after arterial injury. Inhibition by a novel DNA enzyme targeting c-Jun

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2962166-7

7 January 2021

based on heuristic

inferred from DOI database lookup

A general purpose RNA-cleaving DNA enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2962166-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2962166-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2962166-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Interobserver reproducibility of histopathologic prognostic variables in primary cutaneous melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2812%2962166-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0140-6736(12)62166-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23660123%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

Europe PubMed Central

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1 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23660123%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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