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Podosome organization drives osteoclast-mediated bone resorption.
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Europe PubMed Central
PMCID
4198343
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
title
Podosome organization drives osteoclast-mediated bone resorption
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
author
Irma Machuca-Gayet
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2
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Europe PubMed Central
PMCID
4198343
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
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13 March 2020
Anne Blangy
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3
1 reference
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Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
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13 March 2020
author name string
Dan Georgess
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1
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Europe PubMed Central
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4198343
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
Pierre Jurdic
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
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13 March 2020
publication date
1 May 2014
1 reference
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Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
published in
Cell Adhesion and Migration
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stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
volume
8
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
page(s)
191-204
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
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The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts
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6 July 2018
Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption
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6 July 2018
Murine dendritic cell transdifferentiation into osteoclasts is differentially regulated by innate and adaptive cytokines
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6 July 2018
The architecture of the adhesive apparatus of cultured osteoclasts: from podosome formation to sealing zone assembly
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6 July 2018
Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts
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Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling
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Podosome and sealing zone: specificity of the osteoclast model
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6 July 2018
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The molecular dynamics of osteoclast adhesions
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6 July 2018
The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function
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6 July 2018
Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity
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6 July 2018
Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption.
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Apatite-mediated actin dynamics in resorbing osteoclasts
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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
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The origins of osteoclasts
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6 July 2018
Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP
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6 July 2018
Resorbability of bone substitute biomaterials by human osteoclasts
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6 July 2018
Human primary osteoclasts: in vitro generation and applications as pharmacological and clinical assay
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6 July 2018
Integrin activation.
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6 July 2018
Podosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains.
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6 July 2018
Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA.
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6 July 2018
Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin
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6 July 2018
Intracellular membrane trafficking in bone resorbing osteoclasts
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Flt3+ macrophage precursors commit sequentially to osteoclasts, dendritic cells and microglia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Osteoclastic acidification pathways during bone resorption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Microtubule-dependent formation of podosomal adhesion structures in primary human macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Integrins and signaling in osteoclast function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Rho and Rac exert antagonistic functions on spreading of macrophage-derived multinucleated cells and are not required for actin fiber formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
CD44 cell adhesion molecules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
RANK is essential for osteoclast and lymph node development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Osteopetrosis and osteoporosis: two sides of the same coin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Rac-GTPase, osteoclast cytoskeleton and bone resorption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Substrate recognition by osteoclast precursors induces C-src/microtubule association.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Osteoclasts and monocytes have similar cytoskeletal structures and adhesion property in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Identification of gelsolin, a Ca2+-dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
The actin treadmill
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Paxillin: a new vinculin-binding protein present in focal adhesions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Osteoclasts express high levels of pp60c-src in association with intracellular membranes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
6 July 2018
Podosomes are dispensable for osteoclast differentiation and migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Internal dynamics of actin structures involved in the cell motility and adhesion: Modeling of the podosomes at the molecular level.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Genome-wide expression analyses establish dendritic cells as a new osteoclast precursor able to generate bone-resorbing cells more efficiently than monocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Vav3 regulates osteoclast function and bone mass
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
The small GTP-binding protein, rho p21, is involved in bone resorption by regulating cytoskeletal organization in osteoclasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343
retrieved
27 October 2018
Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The origin of dendritic cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Rho-A is critical for osteoclast podosome organization, motility, and bone resorption
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts*1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pediatric bone marrow transplantation for leukemia and aplastic anemia. Report of 222 cases transplanted in a single center
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immature dendritic cell transdifferentiation into osteoclasts: a novel pathway sustained by the rheumatoid arthritis microenvironment
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24714644
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/CAM.27840
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
PMCID
4198343
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
PubMed ID
24714644
1 reference
stated in
Europe PubMed Central
PMCID
4198343
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
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