(Q50752062)

18 March 2018

title

p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption. (English)

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18 March 2018

11

Sachiko Seo

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author name string

Yoshie Nagai

1

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Kenji Osawa

2

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Hidefumi Fukushima

3

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Yukihiko Tamura

4

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Kazuhiro Aoki

5

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Keiichi Ohya

6

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Hisataka Yasuda

7

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Hisako Hikiji

8

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Mariko Takahashi

9

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Yuji Seta

10

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Mineo Kurokawa

12

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Shigeaki Kato

13

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Hiroaki Honda

14

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Ichiro Nakamura

15

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Kenshi Maki

16

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Eijiro Jimi

17

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publication date

1 December 2013

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Journal of Bone and Mineral Research

published in

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18 March 2018

volume

28

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issue

12

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page(s)

2449-2462

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18 March 2018

Regulation of bone mass by serotonin: molecular biology and therapeutic implications

cites work

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New insights into osteoclastogenic signaling mechanisms

21 January 2018

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Regulation of osteoclast function

21 January 2018

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Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

21 January 2018

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The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.

21 January 2018

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Blimp1-mediated repression of negative regulators is required for osteoclast differentiation

21 January 2018

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Tyrosine phosphorylation of p130Cas is involved in actin organization in osteoclasts.

21 January 2018

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Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro.

21 January 2018

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Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption.

21 January 2018

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A possible mechanism of the specific action of bisphosphonates on osteoclasts: tiludronate preferentially affects polarized osteoclasts having ruffled borders

21 January 2018

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Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

21 January 2018

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c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

21 January 2018

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

21 January 2018

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Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

21 January 2018

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Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts

21 January 2018

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Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

21 January 2018

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Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts

21 January 2018

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Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

21 January 2018

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p130Cas: a versatile scaffold in signaling networks

21 January 2018

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Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance

21 January 2018

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Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts

21 January 2018

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Paxillin contracts the osteoclast cytoskeleton

21 January 2018

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Vav3 regulates osteoclast function and bone mass

21 January 2018

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Mammalian Rho GTPases: new insights into their functions from in vivo studies

21 January 2018

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Rac deletion in osteoclasts causes severe osteopetrosis

21 January 2018

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Signaling to actin dynamics

21 January 2018

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

21 January 2018

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The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts

21 January 2018

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Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex

21 January 2018

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Decreased c-Src expression enhances osteoblast differentiation and bone formation

21 January 2018

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Phosphorylation of p130Cas initiates Rac activation and membrane ruffling

21 January 2018

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uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.

21 January 2018

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Arp2/3 complex from Acanthamoeba binds profilin and cross-links actin filaments

21 January 2018

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Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements

21 January 2018

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Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone

21 January 2018

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PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase

21 January 2018

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Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

21 January 2018

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Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JBMR.1936

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18 March 2018

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18 March 2018