(Q29547630)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

23 April 2017

0 references

Rossman KL

1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

23 April 2017

Der CJ

series ordinal

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

23 April 2017

Sondek J

series ordinal

3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

23 April 2017

language of work or name

1 reference

23 April 2017

publication date

February 2005

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

Nature Reviews Molecular Cell Biology

23 April 2017

published in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

23 April 2017

volume

6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

23 April 2017

page(s)

167-80

1 reference

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23 April 2017

issue

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

Rho GTPases and signaling networks

23 April 2017

cites work

1 reference

Rho GTPases and their effector proteins

31 March 2020

1 reference

31 March 2020

Signaling to Rho GTPases

1 reference

The role of Rho in G protein-coupled receptor signal transduction

31 March 2020

1 reference

Rho family proteins in cell adhesion and cell migration.

31 March 2020

1 reference

Function of Rho family proteins in actin dynamics during phagocytosis and engulfment

31 March 2020

1 reference

Rho GTPases in cell biology

31 March 2020

1 reference

Cell migration: Rho GTPases lead the way

31 March 2020

1 reference

31 March 2020

RHO-GTPases and cancer

1 reference

The predicted DBL oncogene product defines a distinct class of transforming proteins

31 March 2020

1 reference

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

31 March 2020

1 reference

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

31 March 2020

1 reference

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

31 March 2020

1 reference

NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

31 March 2020

1 reference

Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

31 March 2020

1 reference

Structure and mutagenesis of the Dbl homology domain

31 March 2020

1 reference

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

31 March 2020

1 reference

A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

31 March 2020

1 reference

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

31 March 2020

1 reference

Crystal Structure of the DH/PH Fragment of Dbs without Bound GTPase

31 March 2020

1 reference

The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids

31 March 2020

1 reference

Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor

31 March 2020

1 reference

Structural analysis of autoinhibition in the Ras activator Son of sevenless

31 March 2020

1 reference

The structural basis of the activation of Ras by Sos

31 March 2020

1 reference

Structural Basis for Activation of ARF GTPase

31 March 2020

1 reference

Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

31 March 2020

1 reference

An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism

31 March 2020

1 reference

Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.

31 March 2020

1 reference

Functional analysis of cdc42 residues required for Guanine nucleotide exchange

31 March 2020

1 reference

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors

31 March 2020

1 reference

RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity

31 March 2020

1 reference

Bacterial expressed DH and DH/PH domains

31 March 2020

1 reference

Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation

31 March 2020

1 reference

Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C.

31 March 2020

1 reference

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

31 March 2020

1 reference

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

31 March 2020

1 reference

The role of the PH domain in the signal-dependent membrane targeting of Sos.

31 March 2020

1 reference

Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting

31 March 2020

1 reference

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

31 March 2020

1 reference

Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.

31 March 2020

1 reference

Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands

31 March 2020

1 reference

Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.

31 March 2020

1 reference

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

31 March 2020

1 reference

Functional analysis of the Caenorhabditis elegans UNC-73B PH domain demonstrates a role in activation of the Rac GTPase in vitro and axon guidance in vivo

31 March 2020

1 reference

Phosphorylation-independent membrane relocalization of ezrin following association with Dbl in vivo

31 March 2020

1 reference

The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin

31 March 2020

1 reference

A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domain

31 March 2020

1 reference

Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis

31 March 2020

1 reference

Lck regulates Vav activation of members of the Rho family of GTPases

31 March 2020

1 reference

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

31 March 2020

1 reference

Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation

31 March 2020

1 reference

Lysophosphatidic acid induces threonine phosphorylation of Tiam1 in Swiss 3T3 fibroblasts via activation of protein kinase C.

31 March 2020

1 reference

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

31 March 2020

1 reference

Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.

31 March 2020

1 reference

p35/cyclin-dependent kinase 5 phosphorylation of ras guanine nucleotide releasing factor 2 (RasGRF2) mediates Rac-dependent Extracellular Signal-regulated kinase 1/2 activity, altering RasGRF2 and microtubule-associated protein 1b distribution in ne

31 March 2020

1 reference

The Rho exchange factor Net1 is regulated by nuclear sequestration

31 March 2020

1 reference

Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis

31 March 2020

1 reference

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

31 March 2020

1 reference

Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1.

31 March 2020

1 reference

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

31 March 2020

1 reference

Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid

31 March 2020

1 reference

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

31 March 2020

1 reference

PAK promotes morphological changes by acting upstream of Rac.

31 March 2020

1 reference

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly

31 March 2020

1 reference

Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.

31 March 2020

1 reference

Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP

31 March 2020

1 reference

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

31 March 2020

1 reference

Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin

31 March 2020

1 reference

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

31 March 2020

1 reference

Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.

31 March 2020

1 reference

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

31 March 2020

1 reference

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF

31 March 2020

1 reference

Mechanisms for reversible regulation between G13 and Rho exchange factors

31 March 2020

1 reference

Regulation of phospholipase C-beta1 by Gq and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation

31 March 2020

1 reference

Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator

31 March 2020

1 reference

A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

31 March 2020

1 reference

EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin

31 March 2020

1 reference

EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells

31 March 2020

1 reference

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

31 March 2020

1 reference

Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.

31 March 2020

1 reference

Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange factor Dbs by Rac1.

31 March 2020

1 reference

Scambio, a novel guanine nucleotide exchange factor for Rho

31 March 2020

1 reference

Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast

31 March 2020

1 reference

Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mating

31 March 2020

1 reference

The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating

31 March 2020

1 reference

A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization

31 March 2020

1 reference

The nucleotide exchange factor Cdc24p may be regulated by auto-inhibition.

31 March 2020

1 reference

Site-specific regulation of the GEF Cdc24p by the scaffold protein Far1p during yeast mating.

31 March 2020

1 reference

Assembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc24p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc24p.

31 March 2020

1 reference

The role of Rho GTPases in disease development

31 March 2020

1 reference

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

31 March 2020

1 reference

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

31 March 2020

1 reference

Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling

31 March 2020

1 reference

Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

31 March 2020

1 reference

Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos

31 March 2020

1 reference

Bcr-Abl variants: biological and clinical aspects

31 March 2020

1 reference

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

31 March 2020

1 reference

Tiam1 mutations in human renal-cell carcinomas

31 March 2020

1 reference

Expression and molecular characterization of alternative transcripts of the ARHGEF5/TIM oncogene specific for human breast cancer

31 March 2020

1 reference

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

31 March 2020

1 reference

Asef, a link between the tumor suppressor APC and G-protein signaling

31 March 2020

1 reference

Mutated APC and Asef are involved in the migration of colorectal tumour cells

31 March 2020

1 reference

Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion

31 March 2020

1 reference

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

31 March 2020

1 reference

Phenotypic and molecular characterisation of the Aarskog–Scott syndrome: a survey of the clinical variability in light of FGD1 mutation analysis in 46 patients

31 March 2020

1 reference

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

31 March 2020

1 reference

Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene

31 March 2020

1 reference

AnALS2gene mutation causes hereditary spastic paraplegia in a Pakistani kindred

31 March 2020

1 reference

Genes in the pX region of human T cell leukemia virus I influence Vav phosphorylation in T cells

31 March 2020

1 reference

Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions

31 March 2020

1 reference

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF

31 March 2020

1 reference

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

31 March 2020

1 reference

MOCA induces membrane spreading by activating Rac1.

31 March 2020

1 reference

Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins

31 March 2020

1 reference

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

31 March 2020

1 reference

DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.

31 March 2020

1 reference

S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells.

31 March 2020

1 reference

SopE and SopE2 from Salmonella typhimurium activate different sets of RhoGTPases of the host cell

31 March 2020

1 reference

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

31 March 2020

1 reference

RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

31 March 2020

1 reference

Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs

31 March 2020

1 reference

Increased neutrophil respiratory burst in bcr-null mutants

31 March 2020

1 reference

Defective dendrite elongation but normal fertility in mice lacking the Rho-like GTPase activator Dbl.

31 March 2020

1 reference

A role for the Ras signalling pathway in synaptic transmission and long-term memory

31 March 2020

1 reference

Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1).

31 March 2020

1 reference

Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis

31 March 2020

1 reference

Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.

31 March 2020

1 reference

Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development

31 March 2020

1 reference

The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties

31 March 2020

1 reference

Ras-guanine nucleotide exchange factor sos2 is dispensable for mouse growth and development

31 March 2020

1 reference

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

31 March 2020

1 reference

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

31 March 2020

1 reference

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

31 March 2020

Identifiers

2 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

370058

1006050511

0 references

370058

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15688002

2 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017