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The role of Rho GTPases in disease development
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
The role of Rho GTPases in disease development
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
author name string
Benjamin Boettner
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
Linda Van Aelst
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
language of work or name
English
0 references
publication date
1 March 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
published in
Gene
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
volume
286
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
page(s)
155-174
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
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Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1
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Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
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PAK3 mutation in nonsyndromic X-linked mental retardation
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7 January 2021
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Mind the GAP, Rho, Rab and GDI.
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Crossref
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Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
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FMR1 protein: conserved RNP family domains and selective RNA binding
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Pak to the future
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A novel regulator of p21-activated kinases
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7 January 2021
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A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins
1 reference
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Crossref
reference URL
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7 January 2021
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Cyclin D1 protein expression and function in human breast cancer
1 reference
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Crossref
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7 January 2021
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Protein kinase C zeta isoform is critical for mitogenic signal transduction
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Missense mutation in PAK3, R67C, causes X-linked nonspecific mental retardation.
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Crossref
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7 January 2021
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Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation
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Crossref
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7 January 2021
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Bacterial toxins inhibiting or activating small GTP-binding proteins
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The ras gene family and human carcinogenesis
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7 January 2021
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Conformational switch and role of phosphorylation in PAK activation
1 reference
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Crossref
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7 January 2021
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Regulatory and signaling properties of the Vav family
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation
1 reference
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Crossref
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7 January 2021
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MRX review
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Crossref
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7 January 2021
based on heuristic
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Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of c-myc expression by PDGF through Rho GTPases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic analysis of metastasis reveals an essential role for RhoC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of Rho function in the thymus is accompanied by the development of thymic lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 protects epithelial cells against anoikis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
alphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
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inferred from DOI database lookup
WASP gene mutations in Wiskott-Aldrich syndrome and X-linked thrombocytopenia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of protein kinase C zeta subspecies blocks the activation of an NF-kappa B-like activity in Xenopus laevis oocytes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tiam1 mutations in human renal-cell carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases are over-expressed in human tumors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple ras effector pathways contribute to G(1) cell cycle progression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic structure, sequence, and refined mapping of the human intersectin gene (ITSN), which encompasses 250 kb on chromosome 21q22.1-->q22.2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases and the actin cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of neocortex in three males with the fragile X syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased expression of a member of the Rho GTPase family, Cdc42Hs, in cells from Tangier disease - the small G protein may play a role in cholesterol efflux
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of invasion of epithelial cells by Tiam1-Rac signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Understanding the molecular basis of fragile X syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of Ras-induced apoptosis by the Rac GTPase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of RhoA mRNA is associated with advanced stage in testicular germ cell tumour
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle targets of Ras/Raf signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A homochiral metal-organic porous material for enantioselective separation and catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bacterial protein toxins targeting rho GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel Cdc42Hs mutant induces cellular transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases in neuronal morphogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Postsynaptic actin and neuronal plasticity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein related to p21-activated kinase (PAK) that is involved in neurogenesis in the Drosophila adult central nervous system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-Specific Activation of Rac Controls Progression through the G1 Phase of the Cell Cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Rac in Tiam1-induced membrane ruffling and invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms that regulate mechanosensory hair cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cdc42 regulates the exit of apical and basolateral proteins from the trans-Golgi network
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of G1 progression, JNK mitogen-activated protein kinase, and actin filament assembly by the exchange factor FGD1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogenesis and endocytosis: What's at the INTERSECTIoN?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mDia mediates Rho-regulated formation and orientation of stable microtubules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras and Rho regulation of the cell cycle and oncogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human intersectin genes and their spliced variants are differentially expressed
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for Rac in Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Rho in Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroanatomy of fragile X syndrome: the posterior fossa
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroanatomy of fragile X syndrome: the temporal lobe
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho proteins: linking signaling with membrane trafficking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erratum: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adult fragile X syndrome. Clinico-neuropathologic findings.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transformation mediated by RhoA requires activity of ROCK kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of myosin light chain kinase by p21-activated kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases: signaling, migration, and invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two novel mutations confirm FGD1 is responsible for the Aarskog syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interdomain binding mediates tumor growth suppression by the NF2 gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IL-1 receptor and Rho directly associate to drive cell activation in inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural mimicry in bacterial virulence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac1 is required for the formation of three germ layers during gastrulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho family GTPases: more than simple switches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Junctophilins: a novel family of junctional membrane complex proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OSP/claudin-11 forms a complex with a novel member of the tetraspanin super family and beta1 integrin and regulates proliferation and migration of oligodendrocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of RhoA, RhoB, RhoG, and Rac1 in fibroblasts from Tangier disease subjects suggests a regulatory role of Rho family proteins in cholesterol efflux
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases and signaling networks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
X-linked thrombocytopenia and Wiskott-Aldrich syndrome are allelic diseases with mutations in the WASP gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The world according to Arp: regulation of actin nucleation by the Arp2/3 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Timing of cyclin D1 expression within G1 phase is controlled by Rho.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
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inferred from DOI database lookup
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific protection against breast cancers by cyclin D1 ablation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new gene involved in X-linked mental retardation identified by analysis of an X;2 balanced translocation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900426-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0378-1119(02)00426-2
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
PubMed ID
11943472
1 reference
stated in
Europe PubMed Central
PubMed ID
11943472
retrieved
3 August 2017
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