(Q42823880)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11703924%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

title

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling (English)

1 reference

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3 December 2019

8

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3 December 2019

author name string

R J Shaw

1

1 reference

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3 December 2019

J G Paez

2

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3 December 2019

M Curto

3

1 reference

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3 December 2019

A Yaktine

4

1 reference

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3 December 2019

W M Pruitt

5

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3 December 2019

I Saotome

6

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3 December 2019

J P O'Bryan

7

1 reference

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3 December 2019

N Ratner

9

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3 December 2019

C J Der

10

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3 December 2019

T Jacks

11

1 reference

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3 December 2019

A I McClatchey

12

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3 December 2019

language of work or name

English

0 references

publication date

1 July 2001

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3 December 2019

number of pages

10

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inferred from page(s)

published in

Developmental Cell

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3 December 2019

volume

1

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3 December 2019

page(s)

63-72

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3 December 2019

issue

1

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Effectors for the Rho GTPases

3 December 2019

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CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

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7 January 2021

ERM-Merlin and EBP50 protein families in plasma membrane organization and function

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7 January 2021

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

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7 January 2021

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

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7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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7 January 2021

Rho proteins induce metastatic properties in vivo

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7 January 2021

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

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7 January 2021

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7 January 2021

The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2.

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7 January 2021

Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesionand spreading

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7 January 2021

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

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7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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7 January 2021

Merlin differs from moesin in binding to F-actin and in its intra- and intermolecular interactions

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7 January 2021

Replacement of threonine 558, a critical site of phosphorylation of moesin in vivo, with aspartate activates F-actin binding of moesin. Regulation by conformational change

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7 January 2021

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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7 January 2021

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

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7 January 2021

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

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7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

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7 January 2021

Signaling to Rho GTPases

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7 January 2021

Stress-activated protein kinases are negatively regulated by cell density.

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7 January 2021

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

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7 January 2021

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

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7 January 2021

Expression level, subcellular distribution and rho-GDI binding affinity of merlin in comparison with Ezrin/Radixin/Moesin proteins

1 reference

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7 January 2021

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

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7 January 2021

Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases

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7 January 2021

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

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7 January 2021

The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation

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7 January 2021

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

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7 January 2021

NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins

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7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

Rho GTPases control polarity, protrusion, and adhesion during cell movement

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7 January 2021

Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth

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7 January 2021

Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures

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7 January 2021

Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells

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7 January 2021

An essential role for Rac in Ras transformation

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7 January 2021

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

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7 January 2021

Farnesyltransferase and geranylgeranyltransferase I inhibitors in cancer therapy: important mechanistic and bench to bedside issues

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7 January 2021

Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion

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7 January 2021

RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts

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7 January 2021

Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli

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7 January 2021

Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression.

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7 January 2021

Interdomain binding mediates tumor growth suppression by the NF2 gene product

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7 January 2021

C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton

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7 January 2021

Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein

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7 January 2021

Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl

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7 January 2021

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

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7 January 2021

Rho GTPases and signaling networks

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7 January 2021

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

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7 January 2021

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

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7 January 2021

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

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7 January 2021

10.1016/S1534-5807(01)00009-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11703924%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference