(Q34347646)

25055199

1 August 2017

title

From genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer (English)

1 reference

1 August 2017

1 reference

1 reference

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Oliver F Bathe

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

22 July 2014

1 reference

1 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

536-560

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 June 2020

copyright license

start time

22 July 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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6 July 2018

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6 July 2018

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ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα.

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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IDO-Mediated Tryptophan Degradation in the Pathogenesis of Malignant Tumor Disease

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Targeting the insulin growth factor pathway in gastrointestinal cancers

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Gene expression meta-analysis identifies VDAC1 as a predictor of poor outcome in early stage non-small cell lung cancer

6 July 2018

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6 July 2018

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The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

6 July 2018

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The Insulin-like Growth Factor Signaling Pathway as a Target for Treatment of Colorectal Carcinoma

6 July 2018

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Microsatellite instability as a marker of prognosis and response to therapy: a meta-analysis of colorectal cancer survival data

6 July 2018

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A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Metabolite profiling of fecal water extracts from human colorectal cancer

6 July 2018

1 reference

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K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Genomic and epigenetic instability in colorectal cancer pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

PTEN and the PI3-kinase pathway in cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Molecular classification and correlates in colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Up-regulation and stabilization of HIF-1alpha in colorectal carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Classification of colorectal cancer based on correlation of clinical, morphological and molecular features

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Metformin and reduced risk of cancer in diabetic patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Systematic review of microsatellite instability and colorectal cancer prognosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Akt stimulates aerobic glycolysis in cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Dysregulated post-transcriptional control of COX-2 gene expression in cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

On respiratory impairment in cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Targeting HIF-1 for cancer therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Therapeutic limitations in tumor-specific CD8+ memory T cell engraftment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Molecular predictors of survival after adjuvant chemotherapy for colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

6 July 2018

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Development of TGF-beta resistance during malignant progression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198916

Molecular predictors of lymph node metastasis in colon cancer: increased risk with decreased thymidylate synthase expression

6 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite Instability

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

MicroRNA signature in metastatic colorectal cancer patients treated with anti-EGFR monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Genetic variation in insulin pathway genes and distal colorectal adenoma risk

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Discrimination of patients with microsatellite instability colon cancer using 1H HR MAS MR spectroscopy and chemometric analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Microsatellite instability in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Seromic profiling of colorectal cancer patients with novel glycopeptide microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Fast targeted multidimensional NMR metabolomics of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Metabolomic NMR Fingerprinting to Identify and Predict Survival of Patients with Metastatic Colorectal Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FGENES5030536

Prognostic value of metabolic parameters in patients with synchronous colorectal cancer liver metastasis following curative-intent colorectal and hepatic surgery

21 January 2018

1 reference

12 December 2020

Serum fatty acid profiling of colorectal cancer by gas chromatography/mass spectrometry

1 reference

12 December 2020

Evaluation of an inflammation-based prognostic score (GPS) in patients undergoing resection for colon and rectal cancer

1 reference

12 December 2020

CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma

1 reference

12 December 2020

Prediction of lymph node metastasis in colorectal carcinoma by expressionof chemokine receptor CCR7

1 reference

12 December 2020

Colonic carcinogenesis in IBD: molecular events

1 reference

12 December 2020

Preoperative but not postoperative systemic inflammatory response correlates with survival in colorectal cancer

1 reference

12 December 2020

Identifiers

DOI

10.3390/GENES5030536

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

25055199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25055199%20AND%20SRC:MED&resulttype=core&format=json