(Q34348211)

1 August 2017

title

Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo and lack immunogenicity per se. (English)

1 reference

1 August 2017

Anne S De Groot

3

0 references

author name string

Yan Su

series ordinal

1

1 reference

1 August 2017

Robert Rossi

series ordinal

2

1 reference

1 August 2017

David W Scott

series ordinal

4

1 reference

1 August 2017

publication date

31 May 2013

1 reference

Journal of Leukocyte Biology

1 August 2017

number of pages

7

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

1 August 2017

volume

94

1 reference

1 August 2017

issue

2

1 reference

1 August 2017

page(s)

377-383

1 reference

Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes

1 August 2017

cites work

1 reference

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Adeno-associated virus mediated delivery of Tregitope 167 ameliorates experimental colitis

6 July 2018

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Tregitope update: mechanism of action parallels IVIg

6 July 2018

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Potential application of tregitopes as immunomodulating agents in multiple sclerosis

6 July 2018

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T cell dynamics during induction of tolerance and suppression of experimental allergic encephalomyelitis

6 July 2018

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B-Cell Gene Therapy for Tolerance Induction: Host but Not Donor B-Cell Derived IL-10 is Necessary for Tolerance

6 July 2018

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Current landscape for T-cell targeting in autoimmunity and transplantation

6 July 2018

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B cells "transduced" with TAT-fusion proteins can induce tolerance and protect mice from diabetes and EAE

6 July 2018

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B-cell delivered gene therapy for tolerance induction: role of autoantigen-specific B cells

6 July 2018

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Can we prevent immunogenicity of human protein drugs?

6 July 2018

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Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714563

B cells induce tolerance by presenting endogenous peptide-IgG on MHC class II molecules via an IFN-gamma-inducible lysosomal thiol reductase-dependent pathway

6 July 2018

1 reference

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6 July 2018

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6 July 2018

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Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

6 July 2018

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6 July 2018

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Mechanisms of gene therapy for tolerance: B7 signaling is required for peptide-IgG gene-transferred tolerance induction

6 July 2018

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Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins

6 July 2018

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Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

6 July 2018

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Natural versus adaptive regulatory T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714563

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

6 July 2018

1 reference

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Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases

6 July 2018

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Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis

6 July 2018

1 reference

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Induction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: the IgG scaffold is important for induction and maintenance of immune hyporesponsiveness

6 July 2018

1 reference

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Epitope-specific tolerance induction with an engineered immunoglobulin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3714563

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6 July 2018

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B-cell based gene therapy for autoimmune diseases

21 January 2018

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A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0912441

Tolerance induction via a B-cell delivered gene therapy-based protocol: optimization and role of the Ig scaffold

21 January 2018

1 reference

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Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis

21 January 2018

1 reference

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CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23729499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23729499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1189/JLB.0912441

1 reference

1 August 2017

1 reference

1 August 2017

1 reference